Shiferaw Kasiye, Mengistie Bezatu, Gobena Tesfaye, Dheresa Merga, Seme Assefa
School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
School of Public Health, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Front Pediatr. 2022 May 23;10:875652. doi: 10.3389/fped.2022.875652. eCollection 2022.
The Sustainable Development Goals specifically target a reduction in neonatal mortality rates. However, the highest neonatal mortality rates occur in sub-Saharan Africa, including Ethiopia. Although several factors contributing to these high rates have been explored, there continues to be a general dearth of studies and inconsistencies of factors to understand the problem. Therefore, this study aimed to identify the prevalence and factors associated with neonatal mortality in Ethiopia.
A panel study was conducted among 2,855 pregnant or recently postpartum women selected using the multistage cluster sampling technique from October 2019 to September 2020. Data were collected by experienced and trained female resident enumerators and coded, cleaned, and analyzed using STATA version 16.1 software. We used the Kaplan-Meier survival curve to show the pattern of neonatal deaths during the first 28 days of life. Frequencies and rates were reported along with the percentages and using a 95% confidence interval, respectively. The Cox proportional hazard regression model was used to explore the association of explanatory and outcome variables. Finally, an adjusted hazard ratio with a 95% confidence interval was used to report the results, with a < 0.05 to declare statistical significance.
The neonatal mortality rate was 26.84 (95% CI: 19.43, 36.96) per 1,000 live births. Neonates born to rural resident mothers (AHR = 2.18, 95% CI: 1.05, 4.54), mothers of advanced age (AHR = 2.49, 95% CI: 1.19, 5.21), and primipara mothers (AHR = 3.16, 95% CI: 1.52, 6.60) had a higher hazard of neonatal mortality. However, neonates born to women who attended technical and vocational level education (AHR = 0.08, 95% CI: 0.01, 0.62) had a lower hazard of neonatal mortality.
The neonatal mortality rate in Ethiopia is high, with increased risk among specific subsets of the population. The findings highlight that neonatal survival can be improved through tailored interventions for rural residents, emerging regions, and primipara women by improving female education and avoiding pregnancy at an advanced maternal age to achieve Sustainable Development Goal target 3.2.
可持续发展目标特别旨在降低新生儿死亡率。然而,撒哈拉以南非洲地区,包括埃塞俄比亚,新生儿死亡率最高。尽管已经探究了导致这些高死亡率的几个因素,但对于理解该问题的研究仍然普遍匮乏,且因素存在不一致性。因此,本研究旨在确定埃塞俄比亚新生儿死亡率的患病率及相关因素。
2019年10月至2020年9月,采用多阶段整群抽样技术,对2855名孕妇或近期产后妇女进行了一项队列研究。数据由经验丰富且经过培训的女性驻地调查员收集,并使用STATA 16.1软件进行编码、清理和分析。我们使用Kaplan-Meier生存曲线来展示出生后前28天内新生儿死亡的模式。分别报告频率和比率以及百分比,并使用95%置信区间。使用Cox比例风险回归模型来探究解释变量和结果变量之间的关联。最后,使用带有95%置信区间的调整后风险比来报告结果,P<0.05表示具有统计学意义。
每1000例活产儿的新生儿死亡率为26.84(95%CI:19.43,36.96)。农村居民母亲所生新生儿(调整后风险比=2.18,95%CI:1.05,4.54)、高龄母亲所生新生儿(调整后风险比=2.49,95%CI:1.19,5.21)以及初产妇所生新生儿(调整后风险比=3.16,95%CI:1.52,6.60)的新生儿死亡风险更高。然而,接受技术和职业教育水平的女性所生新生儿(调整后风险比=0.08,95%CI:0.01,0.62)的新生儿死亡风险较低。
埃塞俄比亚的新生儿死亡率很高,特定人群子集的风险增加。研究结果表明,通过为农村居民、新兴地区和初产妇提供量身定制的干预措施,提高女性教育水平并避免高龄孕产妇怀孕,可改善新生儿存活率,以实现可持续发展目标3.2。