Elgassim Mohamed Abdelgadir M, Saied Amin Saied Sanosi, Mustafa Moayad A, Abdelrahman Amro, AlJaufi Ibtesam, Salem Waleed
Emergency Medicine, Hamad General Hospital, Doha, QAT.
Internal Medicine, Hamad General Hospital, Doha, QAT.
Cureus. 2022 May 4;14(5):e24728. doi: 10.7759/cureus.24728. eCollection 2022 May.
Ventricular fibrillation is not known as a complication of metronidazole poisoning. Although some arrhythmias have been reported as a complication of metronidazole intake while taking antiarrhythmic medications, most such arrhythmias are possibly related to co-ingestion of drugs with metronidazole as it affects the metabolism of these drugs. In this case, ventricular fibrillation occurred in a young patient without preexisting medical conditions or any other known drug ingestion, which was never been reported before. We present a case of an 18-year-old male brought in by the ambulance service after attempting to end his life by overdosing on metronidazole. While being transported he developed ventricular fibrillation and received an electric shock, which reverted the episode. Laboratory investigations did not show any clear cause that might have precipitated his arrhythmia.
室颤并非已知的甲硝唑中毒并发症。尽管有报道称在服用抗心律失常药物时，甲硝唑摄入会引发一些心律失常作为并发症，但大多数此类心律失常可能与甲硝唑和其他药物共同服用有关，因为甲硝唑会影响这些药物的代谢。在本病例中，一名无基础疾病且无其他已知药物摄入史的年轻患者发生了室颤，这在此前从未有过报道。我们报告一例18岁男性病例，该患者因过量服用甲硝唑试图自杀后被救护车送来。在转运途中他发生了室颤并接受了电击，电击使发作得以逆转。实验室检查未显示任何可能引发其心律失常的明确原因。
