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病例报告:一名复发缓解型多发性硬化症患者接受富马酸二甲酯治疗后出现巴洛同心性硬化样病变

Case Report: Baló's Concentric Sclerosis-Like Lesion in a Patient With Relapsing-Remitting Multiple Sclerosis Treated With Dimethyl Fumarate.

作者信息

Kania Karolina, Ambrosius Wojciech, Kozubski Wojciech, Kalinowska Alicja

机构信息

Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.

Division of Neurochemistry and Neuropathology, Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

Front Neurol. 2022 May 23;13:891113. doi: 10.3389/fneur.2022.891113. eCollection 2022.

Abstract

Baló's concentric sclerosis (BCS) is a rare demyelinating disorder characterized by acute or subacute neurological symptoms associated with characteristic lesions of concentric onion skin appearance on MRI images and in pathology. The connection between BCS and classic MS is still a subject of debates. Our report presents a case of a patient who developed a symptomatic Baló-like lesion following several years of classical relapsing-remitting multiple sclerosis treated with dimethyl fumarate.

摘要

巴洛同心性硬化(BCS)是一种罕见的脱髓鞘疾病,其特征为急性或亚急性神经症状,与MRI图像及病理学上具有特征性的同心洋葱皮样病变相关。BCS与经典型多发性硬化症之间的联系仍是一个有争议的话题。我们的报告介绍了一例患者,该患者在接受富马酸二甲酯治疗数年的经典复发缓解型多发性硬化症后出现了有症状的巴洛样病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/845a/9168072/315aa685bd40/fneur-13-891113-g0001.jpg

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