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一名年轻成年女性患巴洛同心性硬化样病变的罕见病例。

A Rare Case of a Balo's Concentric Sclerosis-Like Lesion in a Young Adult Woman.

作者信息

Vickaryous Kailee, Poli De Frias Fernando, Gonzalez George A

机构信息

Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, USA.

Internal Medicine, Mount Sinai Medical Center, Miami, USA.

出版信息

Cureus. 2023 Oct 10;15(10):e46803. doi: 10.7759/cureus.46803. eCollection 2023 Oct.

DOI:10.7759/cureus.46803
PMID:37954773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10635639/
Abstract

Balo's concentric sclerosis (BCS) is a rare demyelinating disorder of the central nervous system (CNS). Distinguishing BCS from other demyelinating disorders such as multiple sclerosis (MS) or from neoplasms can be difficult clinically; however, MRI aids in the identification of the disease. We describe the case of a 37-year-old female presenting with sudden onset of neurologic symptoms associated with a solitary rounded white-matter lesion suggestive of BCS. This rare disorder can present with heterogenous symptoms, imaging findings, and response to treatment. Furthermore, more in-depth analysis of the presentations and treatment outcomes of BCS are necessary in order to create a more robust plan of care.

摘要

巴洛同心圆性硬化(BCS)是一种罕见的中枢神经系统(CNS)脱髓鞘疾病。临床上,将BCS与其他脱髓鞘疾病如多发性硬化症(MS)或肿瘤区分开来可能很困难;然而,磁共振成像(MRI)有助于该疾病的识别。我们描述了一例37岁女性病例,该患者突然出现神经系统症状,并伴有一个提示BCS的孤立圆形白质病变。这种罕见疾病可表现出多样的症状、影像学表现及对治疗的反应。此外,有必要对BCS的临床表现和治疗结果进行更深入的分析,以制定更完善的护理方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43db/10635639/2f718bc7c219/cureus-0015-00000046803-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43db/10635639/3c043af4e34b/cureus-0015-00000046803-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43db/10635639/2f718bc7c219/cureus-0015-00000046803-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43db/10635639/3c043af4e34b/cureus-0015-00000046803-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43db/10635639/2f718bc7c219/cureus-0015-00000046803-i02.jpg

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本文引用的文献

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Biomedicines. 2022 Aug 21;10(8):2041. doi: 10.3390/biomedicines10082041.
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Clinical and Radiologic Features, Pathology, and Treatment of Baló Concentric Sclerosis.Baló 同心圆性硬化的临床和放射学特征、病理学和治疗。
Neurology. 2021 Jul 27;97(4):e414-e422. doi: 10.1212/WNL.0000000000012230. Epub 2021 May 19.
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Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition.
全球多发性硬化症患病率上升:第三版多发性硬化症图谱的见解。
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Concurrence of juvenile idiopathic arthritis and primary demyelinating disease in a young child.幼年特发性关节炎与小儿原发性脱髓鞘疾病的并发。
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Baló's concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures.巴洛氏同心性硬化症在免疫学上有别于多发性硬化症:近 150 次腰椎穿刺的回顾性分析结果。
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8
Atypical idiopathic inflammatory demyelinating lesions: prognostic implications and relation to multiple sclerosis.非典型特发性炎症性脱髓鞘病变:预后意义及其与多发性硬化的关系。
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Brain. 2005 May;128(Pt 5):979-87. doi: 10.1093/brain/awh457. Epub 2005 Mar 17.