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以孤立性肾肿块为表现的转移性乳头状甲状腺癌:病例报告及文献复习

Metastatic papillary thyroid carcinoma presenting as an isolated renal mass: Case report and review of the literature.

作者信息

Thompson David, Hwang Alex, Waldorf Benjamin

机构信息

Department of Urology, Erlanger Health System, 979 East Third Street, Suite C-925, Chattanooga, TN, 37403, USA.

出版信息

Urol Case Rep. 2022 Apr 16;43:102087. doi: 10.1016/j.eucr.2022.102087. eCollection 2022 Jul.

DOI:10.1016/j.eucr.2022.102087
PMID:35677474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9168477/
Abstract

Distant metastasis of Papillary Thyroid Cancer (PTC) to the kidney(s), while rare, has been observed, with approximately 30 cases described in the literature. We present the case of a 28-year-old male who was diagnosed with metastatic PTC following resection of a solitary renal mass. Pathological analysis of the thyroid gland following subsequent thyroidectomy revealed positive regional lymph nodes consistent with metastatic PTC, however, no evidence of malignancy was identified in the thyroid gland. To our knowledge, this is the only known case of metastatic PTC involving the kidney in which no primary lesion was found in the thyroid gland.

摘要

甲状腺乳头状癌(PTC)远处转移至肾脏虽罕见,但已有相关报道,文献中描述了约30例病例。我们报告一例28岁男性病例,该患者在切除孤立性肾肿块后被诊断为转移性PTC。随后甲状腺切除术后甲状腺的病理分析显示区域淋巴结阳性,符合转移性PTC,但甲状腺内未发现恶性证据。据我们所知,这是唯一一例已知的转移性PTC累及肾脏且甲状腺内未发现原发灶的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/9a27ce0a9524/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/ed38d5ac1373/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/d8c89fa766d1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/9a27ce0a9524/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/ed38d5ac1373/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/d8c89fa766d1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/9168477/9a27ce0a9524/gr3.jpg

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本文引用的文献

1
Occult Papillary Thyroid Carcinoma without Detection of the Primary Tumor on Preoperative Ultrasonography or Postoperative Pathological Examination: A Case Report.术前超声检查或术后病理检查均未发现原发肿瘤的隐匿性甲状腺乳头状癌:一例报告
Case Rep Oncol. 2020 Feb 11;13(1):105-112. doi: 10.1159/000505831. eCollection 2020 Jan-Apr.
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Renal metastases as the initial presentation of papillary thyroid carcinoma: A case report and literature review.肾转移作为甲状腺乳头状癌的首发表现:一例病例报告及文献综述
Mol Clin Oncol. 2017 Jun;6(6):821-824. doi: 10.3892/mco.2017.1243. Epub 2017 May 8.
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Standard and emerging therapies for metastatic differentiated thyroid cancer.
转移性分化型甲状腺癌的标准和新兴疗法。
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Differentiated thyroid cancer presenting initially with distant metastasis.初诊时即出现远处转移的分化型甲状腺癌。
Am J Surg. 1997 Nov;174(5):474-6. doi: 10.1016/s0002-9610(97)00158-x.