Department of Mental Health, Moi Teaching & Referral Hospital, Eldoret, Kenya.
Department of Mental Health, Mbagathi Hospital, Nairobi, Kenya.
PLoS One. 2022 Jun 9;17(6):e0269340. doi: 10.1371/journal.pone.0269340. eCollection 2022.
The burden of substance use in Kenya is significant. The objective of this study was to systematically summarize existing literature on substance use in Kenya, identify research gaps, and provide directions for future research.
This systematic review was conducted in line with the PRISMA guidelines. We conducted a search of 5 bibliographic databases (PubMed, PsychINFO, Web of Science, Cumulative Index of Nursing and Allied Professionals (CINAHL) and Cochrane Library) from inception until 20 August 2020. In addition, we searched all the volumes of the official journal of the National Authority for the Campaign Against Alcohol & Drug Abuse (the African Journal of Alcohol and Drug Abuse). The results of eligible studies have been summarized descriptively and organized by three broad categories including: studies evaluating the epidemiology of substance use, studies evaluating interventions and programs, and qualitative studies exploring various themes on substance use other than interventions. The quality of the included studies was assessed with the Quality Assessment Tool for Studies with Diverse Designs.
Of the 185 studies that were eligible for inclusion, 144 investigated the epidemiology of substance use, 23 qualitatively explored various substance use related themes, and 18 evaluated substance use interventions and programs. Key evidence gaps emerged. Few studies had explored the epidemiology of hallucinogen, prescription medication, ecstasy, injecting drug use, and emerging substance use. Vulnerable populations such as pregnant women, and persons with physical disability had been under-represented within the epidemiological and qualitative work. No intervention study had been conducted among children and adolescents. Most interventions had focused on alcohol to the exclusion of other prevalent substances such as tobacco and cannabis. Little had been done to evaluate digital and population-level interventions.
The results of this systematic review provide important directions for future substance use research in Kenya.
PROSPERO: CRD42020203717.
肯尼亚的物质使用负担很重。本研究的目的是系统总结肯尼亚物质使用的现有文献，确定研究空白，并为未来的研究提供方向。
本系统评价按照 PRISMA 指南进行。我们从创建到 2020 年 8 月 20 日，在 5 个文献数据库（PubMed、PsychINFO、Web of Science、Cumulative Index of Nursing and Allied Professionals (CINAHL) 和 Cochrane Library）中进行了搜索。此外，我们还搜索了国家打击酒精和药物滥用运动管理局（《非洲酒精和药物滥用杂志》）官方期刊的所有卷册。合格研究的结果已进行了描述性总结，并按三个广泛的类别进行了组织，包括：评估物质使用流行病学的研究、评估干预措施和方案的研究以及探索物质使用干预措施以外的各种主题的定性研究。使用不同设计研究质量评估工具评估纳入研究的质量。
在 185 项符合纳入标准的研究中，144 项研究调查了物质使用的流行病学，23 项研究定性探讨了各种物质使用相关主题，18 项研究评估了物质使用干预措施和方案。出现了关键的证据空白。很少有研究探讨过迷幻剂、处方药物、摇头丸、注射吸毒和新兴物质使用的流行病学。在流行病学和定性工作中，孕妇和身体残疾者等弱势群体代表性不足。没有针对儿童和青少年开展干预研究。大多数干预措施都集中在酒精上，而忽略了其他常见物质，如烟草和大麻。很少有人致力于评估数字和人群层面的干预措施。
本系统评价的结果为肯尼亚未来的物质使用研究提供了重要方向。
PROSPERO：CRD42020203717。
