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难民和移民人群中的结核病:系统评价。

Tuberculosis among refugees and migrant populations: Systematic review.

机构信息

Ethiopian Public Health Institute (EPHI), Addis Ababa, Ethiopia.

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

PLoS One. 2022 Jun 9;17(6):e0268696. doi: 10.1371/journal.pone.0268696. eCollection 2022.

Abstract

Tuberculosis (TB) is an important cause of morbidity and mortality among refugees and migrant populations. These groups are among the most vulnerable populations at increased risk of developing TB. However, there is no systematic review that attempts to summarize TB among refugees and migrant populations. This study aimed to summarize evidence on the magnitude of TB among refugees and migrant populations. The findings of this review will provide evidence to improve TB prevention and control policies in refugees and migrants in refugee camps and in migrant-hosting countries. A systematic search was done to retrieve the articles published from 2014 to 2021 in English language from electronic databases. Key searching terms were used in both free text and Medical Subject Heading (MeSH). Articles which had reported the magnitude of TB among refugees and migrant populations were included in the review. We assessed the risk of bias, and quality of the included studies with a modified version of the Newcastle-Ottawa Scale (NOS). Included studies which had reported incidence or prevalence data were eligible for data synthesis. The results were shown as summary tables. In the present review, more than 3 million refugees and migrants were screened for TB with the data collection period between 1991 and 2017 among the included studies. The incidence and prevalence of TB ranged from 19 to 754 cases per 100,000 population and 18.7 to 535 cases per 100,000 population respectively among the included studies. The current findings show that the most reported countries of origin in TB cases among refugees and migrants were from Asia and Africa; and the incidence and prevalence of TB among refugees and migrant populations is higher than in the host countries. This implies the need to implement and improve TB prevention and control in refugees and migrant populations globally. Trial registration: The protocol of this review was registered on PROSPERO (International prospective register of systematic reviews) with ID number, CRD42020157619.

摘要

结核病(TB)是难民和移民人群发病率和死亡率的重要原因。这些人群是感染结核病风险增加的最脆弱人群之一。然而,目前尚无系统评价试图总结难民和移民人群中的结核病情况。本研究旨在总结难民和移民人群中结核病的规模证据。本综述的结果将为改善难民营和移民收容国的难民和移民中的结核病预防和控制政策提供证据。我们从电子数据库中以英文语言检索了 2014 年至 2021 年发表的文章,进行了系统搜索。在自由文本和医学主题词(MeSH)中都使用了关键搜索词。本综述纳入了报告难民和移民人群中结核病规模的文章。我们使用改良的纽卡斯尔-渥太华量表(NOS)评估了纳入研究的偏倚风险和质量。纳入的研究报告了发病率或患病率数据,有资格进行数据综合。结果以汇总表的形式呈现。在本综述中,在纳入的研究中,有超过 300 万难民和移民接受了结核病筛查,数据收集时间为 1991 年至 2017 年。纳入的研究中,结核病的发病率和患病率范围分别为每 100,000 人口 19 至 754 例和每 100,000 人口 18.7 至 535 例。目前的研究结果表明,在难民和移民中的结核病病例中,报告最多的原籍国是亚洲和非洲;难民和移民人群中的结核病发病率和患病率高于收容国。这意味着需要在全球范围内实施和加强难民和移民人群中的结核病预防和控制。试验注册:本综述的方案已在 PROSPERO(国际前瞻性系统评价注册库)上注册,注册号为 ID number,CRD42020157619。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01b6/9182295/740f3c9f3675/pone.0268696.g001.jpg

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