Minias Alina, Kuzioła Magdalena, Ahmeti Florin, Mehmeti Nazmi, Jerliu Blendi, Lila Greta, Miftari Albuena, Shkodra Xhevat, Jakupi Xhevat, Kacaniku Zana, Kozińska Monika, Zabost Anna, Słomka Marcin, Strapagiel Dominik, Dziadek Jarosław, Augustynowicz-Kopeć Ewa, Bajrami Rrezarta
Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
The Bio-Med-Chem Doctoral School of the University of Lodz and Lodz Institutes of the Polish Academy of Sciences, Lodz, Poland.
J Clin Tuberc Other Mycobact Dis. 2025 Jun 7;40:100537. doi: 10.1016/j.jctube.2025.100537. eCollection 2025 Aug.
Tuberculosis incidence in Kosovo is among one of the highest in Europe at 33/100,000 citizens. While World Health Organization encourages epidemiological monitoring of tuberculosis transmission, studies regarding population structure in the Balkan region are limited. Here, we used spoligotyping and whole genome sequencing to describe the variation of strains circulating in Kosovo. We used samples isolated from patients in the period 2021/2022. We found that the vast majority of isolated strains belonged to spoligotype based Euro-American lineage, five strains belonged to East-Asian lineage, and one was . We described the general characteristics of the population in our study and identified chains of transmission based on whole genome sequencing data of selected samples. Our data will be a reference point for subsequent studies of population in Kosovo.
科索沃的结核病发病率在欧洲位居前列，为每10万公民中有33例。虽然世界卫生组织鼓励对结核病传播进行流行病学监测，但关于巴尔干地区人口结构的研究却很有限。在此，我们采用 spoligotyping技术和全基因组测序来描述在科索沃流行的菌株的变异情况。我们使用了2021年/2022年期间从患者身上分离出的样本。我们发现，绝大多数分离出的菌株属于基于spoligotype的欧美谱系，五株属于东亚谱系，还有一株……我们描述了我们研究中该菌群的一般特征，并根据所选样本的全基因组测序数据确定了传播链。我们的数据将为科索沃后续该菌群的研究提供参考依据。
