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用虫草花提取物生物合成铂纳米颗粒：表征、抗氧化活性和抗菌活性。

Biosynthesis of Platinum Nanoparticles with Cordyceps Flower Extract: Characterization, Antioxidant Activity and Antibacterial Activity.

作者信息

Liu Ling, Jing Yun, Guo Ailing, Li Xiaojing, Li Qun, Liu Wukang, Zhang Xinshuai

机构信息

College of Food Science and Technology, Huazhong Agriculture University, Wuhan 430070, China.

Kaibei Technology (Suzhou) Co., Ltd., Suzhou 215000, China.

出版信息

Nanomaterials (Basel). 2022 Jun 2;12(11):1904. doi: 10.3390/nano12111904.

DOI:10.3390/nano12111904
PMID:35683759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9182170/
Abstract

The aim of this work is to develop a green route for platinum nanoparticles (PtNPs) biosynthesized using Cordyceps flower extract and to evaluate their antioxidant activity and antibacterial activity. Different characterization techniques were utilized to characterize the biosynthetic PtNPs. The results showed that PtNPs were spherical particles covered with Cordyceps flower extract. The average particle size of PtNPs in Dynamic Light Scattering was 84.67 ± 5.28 nm, while that of PtNPs in Transmission Electron Microscope was 13.34 ± 4.06 nm. Antioxidant activity of PtNPs was evaluated by DPPH free radical scavenging ability test. The results showed that the antioxidant activity was positively correlated with the concentration of PtNPs, the DPPH scavenging efficiency of PtNPs (0.50-125.00 μg/mL) was 27.77-44.00%. In addition, the morphological changes of four kinds of bacteria (, , , ) exposed to PtNPs were observed by scanning electron microscope. The results showed that the antibacterial activity of PtNPs against Gram-negative bacteria was stronger than that of Gram-positive bacteria.

摘要

这项工作的目的是开发一条利用虫草花提取物生物合成铂纳米颗粒（PtNPs）的绿色路线，并评估其抗氧化活性和抗菌活性。采用了不同的表征技术对生物合成的PtNPs进行表征。结果表明，PtNPs为覆盖有虫草花提取物的球形颗粒。动态光散射法测得PtNPs的平均粒径为84.67±5.28nm，而透射电子显微镜测得的PtNPs平均粒径为13.34±4.06nm。通过DPPH自由基清除能力试验评估PtNPs的抗氧化活性。结果表明，抗氧化活性与PtNPs的浓度呈正相关，PtNPs（0.50 - 125.00μg/mL）的DPPH清除效率为27.77 - 44.00%。此外，通过扫描电子显微镜观察了四种细菌（此处原文缺失细菌名称）暴露于PtNPs后的形态变化。结果表明，PtNPs对革兰氏阴性菌的抗菌活性强于革兰氏阳性菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/f7eaf3e9fab8/nanomaterials-12-01904-g011.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/97e062bb2a82/nanomaterials-12-01904-g006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/c4002d0c35e0/nanomaterials-12-01904-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/735d10daf599/nanomaterials-12-01904-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/f7eaf3e9fab8/nanomaterials-12-01904-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/ac8688222c8f/nanomaterials-12-01904-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/45d49e992176/nanomaterials-12-01904-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/f2e66975ffe2/nanomaterials-12-01904-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/97e062bb2a82/nanomaterials-12-01904-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/c905108a2bbd/nanomaterials-12-01904-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/59e91ea44540/nanomaterials-12-01904-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/c4002d0c35e0/nanomaterials-12-01904-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/735d10daf599/nanomaterials-12-01904-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/9182170/f7eaf3e9fab8/nanomaterials-12-01904-g011.jpg

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