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用于皮肤科和护肤应用的铂基活性成分展望。

An Outlook on Platinum-Based Active Ingredients for Dermatologic and Skincare Applications.

作者信息

Li Shining, Liu Yizhou, Wu Ying, Ren Lu, Lu Yongjie, Yamaguchi Shuji, Lu Qipeng, Hu Chuangang, Li Dongcui, Jiang Naisheng

机构信息

Key Laboratory of Advanced Materials and Devices for Post-Moore Chips, Ministry of Education, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.

Hua An Tang Biotech Group Co., Ltd., Guangzhou 511434, China.

出版信息

Nanomaterials (Basel). 2024 Aug 2;14(15):1303. doi: 10.3390/nano14151303.

DOI:10.3390/nano14151303
PMID:39120408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11314049/
Abstract

Platinum-based materials exhibit a broad spectrum of biological activities, including antioxidant, anti-inflammatory, antimicrobial, and pro-collagen synthesis properties, making them particularly useful for various biomedical applications. This review summarizes the biological effects and therapeutic potential of platinum-based active ingredients in dermatological and skincare applications. We discuss their synthesis methods and their antioxidant, anti-inflammatory, antimicrobial, and collagen synthesis properties, which play essential roles in treating skin conditions including psoriasis and acne, as well as enhancing skin aesthetics in anti-aging products. Safety and sustainability concerns, including the need for green synthesis and comprehensive toxicological assessments to ensure safe topical applications, are also discussed. By providing an up-to-date overview of current research, we aim to highlight both the potential and the current challenges of platinum-based active ingredients in advancing dermatology and skincare solutions.

摘要

铂基材料具有广泛的生物活性，包括抗氧化、抗炎、抗菌和促进胶原蛋白合成的特性，这使得它们在各种生物医学应用中特别有用。本综述总结了铂基活性成分在皮肤科和护肤品应用中的生物学效应和治疗潜力。我们讨论了它们的合成方法以及抗氧化、抗炎、抗菌和胶原蛋白合成特性，这些特性在治疗包括牛皮癣和痤疮在内的皮肤疾病以及增强抗衰老产品的皮肤美观方面发挥着重要作用。还讨论了安全和可持续性问题，包括绿色合成的必要性和全面的毒理学评估，以确保局部应用的安全性。通过提供当前研究的最新概述，我们旨在突出铂基活性成分在推进皮肤科和护肤解决方案方面的潜力和当前挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/b3e61f261b19/nanomaterials-14-01303-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/405f4d869a35/nanomaterials-14-01303-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/3bbd7a862665/nanomaterials-14-01303-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/c5fb190de913/nanomaterials-14-01303-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/a3b36954cbf1/nanomaterials-14-01303-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/375d816ed9c4/nanomaterials-14-01303-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/f72c26e76bed/nanomaterials-14-01303-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/407953139656/nanomaterials-14-01303-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/429ae994cc15/nanomaterials-14-01303-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/72214052c8c2/nanomaterials-14-01303-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/84130deab60a/nanomaterials-14-01303-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/b3e61f261b19/nanomaterials-14-01303-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/405f4d869a35/nanomaterials-14-01303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/0f9c4a1ea43f/nanomaterials-14-01303-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/c89c1d6563b1/nanomaterials-14-01303-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/0f153c80ff24/nanomaterials-14-01303-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/3bbd7a862665/nanomaterials-14-01303-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/c5fb190de913/nanomaterials-14-01303-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/a3b36954cbf1/nanomaterials-14-01303-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/375d816ed9c4/nanomaterials-14-01303-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/f72c26e76bed/nanomaterials-14-01303-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/407953139656/nanomaterials-14-01303-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/429ae994cc15/nanomaterials-14-01303-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/72214052c8c2/nanomaterials-14-01303-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/84130deab60a/nanomaterials-14-01303-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c01/11314049/b3e61f261b19/nanomaterials-14-01303-g014.jpg

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