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用于生物医学应用的铂纳米颗粒的绿色合成

Green Synthesis of Platinum Nanoparticles for Biomedical Applications.

作者信息

Mikhailova Ekaterina O

机构信息

Institute of Innovation Management, Kazan National Research Technological University, K. Marx Street 68, 420015 Kazan, Russia.

出版信息

J Funct Biomater. 2022 Nov 21;13(4):260. doi: 10.3390/jfb13040260.

Abstract

The diverse biological properties of platinum nanoparticles (PtNPs) make them ideal for use in the development of new tools in therapy, diagnostics, and other biomedical purposes. "Green" PtNPs synthesis is of great interest as it is eco-friendly, less energy-consuming and minimizes the amount of toxic by-products. This review is devoted to the biosynthesis properties of platinum nanoparticles based on living organisms (bacteria, fungi, algae, and plants) use. The participation of various biological compounds in PtNPs synthesis is highlighted. The biological activities of "green" platinum nanoparticles (antimicrobial, anticancer, antioxidant, etc.), the proposed mechanisms of influence on target cells and the potential for their further biomedical application are discussed.

摘要

铂纳米颗粒(PtNPs)具有多种生物学特性,使其成为开发治疗、诊断及其他生物医学用途新工具的理想选择。“绿色”合成PtNPs备受关注,因为它环保、能耗低且能将有毒副产物的量降至最低。本综述致力于基于生物体(细菌、真菌、藻类和植物)利用的铂纳米颗粒的生物合成特性。重点介绍了各种生物化合物在PtNPs合成中的参与情况。讨论了“绿色”铂纳米颗粒的生物活性(抗菌、抗癌、抗氧化等)、对靶细胞的潜在影响机制及其进一步生物医学应用的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1383/9680517/fe50a8a949b9/jfb-13-00260-g001.jpg

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