Marine Chemistry Department, Faculty of Marine Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Department of Chemistry, College of Science and Art, King Abdulaziz University, Jeddah 22254, Saudi Arabia.
Molecules. 2022 May 25;27(11):3415. doi: 10.3390/molecules27113415.
The aim of this study was to determine the compositions of carbohydrates, phenolic compounds, fatty acids (FAs), and amino acids (AAs) of four Rea Sea halophytes: , , , and . The results showed that and were rich in gallic acid with 41.72 and 47.48 mg/g, respectively, while was rich in naringenin with 11.88 mg/g. The polysaccharides of the four species were mainly composed of galactose (54.74%) in , mannose (44.15%) in , glucose and ribose (33 and 26%, respectively) in , and arabinose and glucose (36.67 and 31.52%, respectively) in . Glutamic acid and aspartic acid were the major AAs in all halophyte species with 50-63% and 10-22% of the total AAs, respectively. The proportion of unsaturated fatty acids (UFA) of the four species was 42.18-55.33%, comprised mainly of linolenic acid (15.54-28.63%) and oleic acid (5.68-22.05%), while palmitic acid (23.94-49.49%) was the most abundant saturated fatty acid (SFA). Phytol and 9,19-cyclolanost-24-en-3β-ol represented the major unsaponifiable matter (USM) constituents of and with proportions 42.44 and 44.11%, respectively. The phenolic fraction of and demonstrated noteworthy antioxidant activity with IC values of 9.0 and 8.0 μg/mL, respectively, while the FAs fraction of exhibited potent cytotoxic activity against Huh-7, A-549, and Caco-2 cancer cell lines with IC values of 7.4, 10.8, and 11.8 μg/mL, respectively. Our results indicate that these plants may be considered a source of naturally occurring compounds with antioxidant and anticancer effects that could be suitable for future applications.
本研究旨在确定四种 Rea 海盐水生植物： 、 、 和 中的碳水化合物、酚类化合物、脂肪酸 (FA) 和氨基酸 (AA) 的组成。结果表明， 和 富含没食子酸，分别为 41.72 和 47.48 mg/g，而 富含柚皮素，为 11.88 mg/g。四种物种的多糖主要由 （54.74%）组成 （44.15%）、 （33%和 26%）、 （36.67%和 31.52%）。谷氨酸和天冬氨酸是所有盐生植物物种中的主要氨基酸，分别占总氨基酸的 50-63%和 10-22%。四种物种的不饱和脂肪酸 (UFA) 比例为 42.18-55.33%，主要由亚麻酸（15.54-28.63%）和油酸（5.68-22.05%）组成，而棕榈酸（23.94-49.49%）是最丰富的饱和脂肪酸 (SFA)。植醇和 9,19-环羊毛甾-24-烯-3β-醇分别代表 和 中主要的不可皂化物 (USM) 成分，比例分别为 42.44%和 44.11%。 和 的酚类部分表现出显著的抗氧化活性，IC 值分别为 9.0 和 8.0 μg/mL，而 的 FA 部分对 Huh-7、A-549 和 Caco-2 癌细胞系表现出强烈的细胞毒性活性，IC 值分别为 7.4、10.8 和 11.8 μg/mL。我们的研究结果表明，这些植物可能被视为具有抗氧化和抗癌作用的天然化合物的来源，可能适合未来的应用。
