Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Nutr Rev. 2022 Sep 5;80(10):2051-2063. doi: 10.1093/nutrit/nuac027.
Several observational and experimental studies have been conducted to evaluate the effects of pistachio intake on metabolic syndrome (MetS); however, the results are inconsistent.
This systematic review and meta-analysis were performed on data from randomized controlled trials (RCTs) to determine the effect of pistachio consumption on MetS components.
The PubMed, Scopus, Google Scholar and Web of Science databases were searched from 1986 to 2021.
English-language RCTs on pistachio intake were included that provided outcomes on hypertension, hyperglycemia, hypertriglyceridemia, and high-density lipoprotein (HDL).
Results are presented as pooled mean differences (MDs) between intervention and control groups with 95%CI reported for each of the components.
Seventeen RCTs including 940 adults met the inclusion criteria for this systematic review and meta-analysis. Pistachio supplementation significantly reduced systolic blood pressure (BP; MD, -2.89 mmHg, 95%CI: -4.11 to -1.67; P < 0.001), triglycerides (MD, -16.76 mg/dL, 95%CI: -16.89 to -16.64; P < 0.001), fasting blood glucose (MD, -3.62 mg/dL, 95%CI: -6.45 to -0.8; P < 0.001,) and increased HDL (MD, 1.43 mg/dL, 95%CI: 1.39 to 1.47; P < 0.001) levels. However, there were not observed considerable changes in waist circumference, diastolic BP, and body mass index.
The results of this research show that pistachio consumption could improve some MetS components, including systolic blood pressure, triglyceride, fasting blood glucose, and HDL levels, without affecting anthropometric indices and diastolic BP.
已经进行了几项观察性和实验性研究，以评估开心果摄入对代谢综合征（MetS）的影响；然而，结果并不一致。
对随机对照试验（RCT）的数据进行系统评价和荟萃分析，以确定开心果消费对 MetS 成分的影响。
从 1986 年到 2021 年，检索了 PubMed、Scopus、Google Scholar 和 Web of Science 数据库。
纳入了关于开心果摄入量的英语 RCT，这些 RCT 提供了高血压、高血糖、高三酰甘油血症和高密度脂蛋白（HDL）的结果。
结果以干预组和对照组之间的汇总均数差值（MD）表示，并为每个成分报告了 95%CI。
这项系统评价和荟萃分析共纳入了 17 项 RCT，涉及 940 名成年人。开心果补充剂可显著降低收缩压（BP；MD，-2.89mmHg，95%CI：-4.11 至-1.67；P<0.001）、三酰甘油（MD，-16.76mg/dL，95%CI：-16.89 至-16.64；P<0.001）、空腹血糖（MD，-3.62mg/dL，95%CI：-6.45 至-0.8；P<0.001）和增加高密度脂蛋白（HDL）（MD，1.43mg/dL，95%CI：1.39 至 1.47；P<0.001）水平。然而，腰围、舒张压和体重指数没有观察到明显变化。
这项研究的结果表明，开心果的摄入可以改善一些 MetS 成分，包括收缩压、三酰甘油、空腹血糖和 HDL 水平，而不影响人体测量指数和舒张压。
