MSU-DOE Plant Research Laboratory, Plant Resilience Institute, and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.
J Exp Bot. 2023 Jan 11;74(2):510-519. doi: 10.1093/jxb/erac254.
Rubisco is possibly the most important enzyme on Earth, certainly in terms of amount. This review describes the initial reports of ribulose 1,5-bisphosphate carboxylating activity. Discoveries of core concepts are described, including its quaternary structure, the requirement for post-translational modification, and its role as an oxygenase as well as a carboxylase. Finally, the requirement for numerous chaperonins for assembly of rubisco in plants is described.
核酮糖-1,5-二磷酸羧化酶/加氧酶可能是地球上最重要的酶,至少就其含量而言是这样的。本综述描述了最初关于核酮糖 1,5-二磷酸羧化/加氧酶活性的报道。介绍了核心概念的发现,包括其四级结构、翻译后修饰的要求,以及其作为加氧酶和羧化酶的作用。最后,还描述了植物中组装核酮糖-1,5-二磷酸羧化酶/加氧酶所需的许多伴侣蛋白。