Moshirfar Majid, Tukan Alyson N, Bundogji Nour, Ronquillo Yasmyne C
Hoopes Vision Research Center, Hoopes Vision, 11820 S. State Street Suite #200, Draper, UT, 84020, USA.
John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA.
Ophthalmol Ther. 2022 Aug;11(4):1301-1307. doi: 10.1007/s40123-022-00524-9. Epub 2022 Jun 11.
Charcot-Marie-Tooth (CMT) disease is the most common inherited polyneuropathy, with a characteristic phenotype of distal muscle weakness, atrophy, and sensory loss. Variable ocular involvement has been documented in patients with CMT, with optic atrophy as the most frequently reported symptom. Although the Charcot-Marie-Tooth Association has generally deemed laser-assisted in situ keratomileuses (LASIK) a safe option for patients with CMT, reports of corneal refractive surgery are lacking in this patient population. This commentary discusses the current understanding of CMT, including its ocular manifestations, and additional specific testing to consider when evaluating these patients for corneal refractive surgery.
夏科-马里-图思（CMT）病是最常见的遗传性多发性神经病，具有远端肌肉无力、萎缩和感觉丧失的典型表型。CMT患者中已记录到不同程度的眼部受累，其中视神经萎缩是最常报告的症状。尽管夏科-马里-图思协会通常认为准分子激光原位角膜磨镶术（LASIK）对CMT患者是一种安全的选择，但该患者群体缺乏角膜屈光手术的相关报告。本评论讨论了目前对CMT的认识，包括其眼部表现，以及在评估这些患者进行角膜屈光手术时应考虑的其他特定检查。
