伊朗北部马赞达兰省住院磷化锌中毒患者的临床表现和治疗管理。
Clinical manifestations and treatment management of hospitalized patients with zinc phosphide poisoning, Mazandaran Province, Northern Iran.
机构信息
Department of Forensic Medicine and Toxicology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Toxicology and Forensic Medicine Division, Orthopedic Research Center Communicable Diseases Institute, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, P. O box: 48166-33131Sari, Mazandaran, Iran.
出版信息
BMC Emerg Med. 2022 Jun 11;22(1):104. doi: 10.1186/s12873-022-00661-1.
BACKGROUND
Zinc phosphide (ZnP) is a dark gray crystalline compound used as a rodenticide against rodents such as mice. ZnP poisoning may be accidental or suicidal. The aim of this study was to investigate the clinical manifestations and treatment management of hospitalized patients with ZnP poisoning in Mazandaran Province, northern Iran.
METHODS
Between 2013 and 2017, a cross-sectional study was performed on hospitalized patients with ZnP poisoning who were referred to two training hospitals in Mazandaran Province, northern Iran.
RESULTS
A total of 127 patients participated in this trial, including 71 (55.9%) men and 56 (44.1%) women. The patients' average (standard deviation) age was 25.5 (±16.82) years, and it took 2.18 (±2.23) hours to refer them to the hospital. There were 42 (33%) cases with less than one package, 9 (7%) cases with several packages, and 76 (60%) cases with no particular usage.
CONCLUSIONS
This study has shown that ZnP poisoning may be asymptomatic initially or with mild clinical symptoms that may gradually worsen. Therefore, hospitalization and obtaining a history and a careful physical examination should be considered.
背景
磷化锌（ZnP）是一种深灰色结晶化合物，用作灭鼠剂，以消灭老鼠等啮齿动物。ZnP 中毒可能是意外或自杀性的。本研究旨在调查伊朗北部马赞达兰省因 ZnP 中毒住院患者的临床表现和治疗管理。
方法
2013 年至 2017 年，对伊朗北部马赞达兰省两所培训医院收治的 ZnP 中毒住院患者进行了一项横断面研究。
结果
共有 127 名患者参与了这项试验，其中 71 名（55.9%）为男性，56 名（44.1%）为女性。患者的平均（标准差）年龄为 25.5（±16.82）岁，将他们送往医院的时间为 2.18（±2.23）小时。有 42 例（33%）少于 1 包，9 例（7%）几包，76 例（60%）无特殊用途。
结论
本研究表明，ZnP 中毒最初可能无症状或仅有轻微的临床症状，且症状可能逐渐加重。因此，应考虑住院并获取病史和仔细的体格检查。
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