Department of Biochemistry, Devdaha Medical College and Research Institute, Devdaha, Rupandehi, Nepal.
Department of Internal Medicine, Devdaha Medical College and Research Institute, Devdaha, Rupandehi, Nepal.
JNMA J Nepal Med Assoc. 2023 Oct 1;61(266):758-761. doi: 10.31729/jnma.8306.
A triad of lipid and lipoprotein metabolism is known as dyslipidemia. Dyslipidemia is one of the major risk factors for cardiovascular diseases in diabetes mellitus which is a leading cause of morbidity and mortality worldwide. The aim of the study was to find out the prevalence of dyslipidemia among patients with type 2 diabetes mellitus visiting a tertiary care centre.
A descriptive cross-sectional study was conducted in a tertiary care centre among patients with type 2 diabetes mellitus from 18 February 2020 to 18 August 2020 after obtaining ethical clearance from the Institutional Review Committee. Demographic and blood samples were analysed and recorded using validated and calibrated tools. A convenience sampling technique was used. The point estimate was calculated at a 95% Confidence Interval.
Out of 390 patients with type 2 diabetes mellitus, 343 (87.95%) (84.72-91.18, 95% Confidence Interval) had dyslipidemia. The most prevalent dyslipidemia was high low-density lipoprotein cholesterol at 85 (24.78%) followed by mixed dyslipidemia at 305 (88.92%).
The prevalence of dyslipidemia among patients with type 2 diabetes mellitus was found to be higher than studies conducted in similar settings. We recommend regular testing of blood glucose and blood lipid levels for early detection of dyslipidemia and putting them under medical supervision to reduce the unwanted complications of cardiovascular diseases.
cardiovascular disease; dyslipidemia; prevalence; type 2 diabetes mellitus.
脂质和脂蛋白代谢的三联体被称为血脂异常。血脂异常是糖尿病心血管疾病的主要危险因素之一，而糖尿病是全球发病率和死亡率的主要原因之一。本研究的目的是了解在一家三级保健中心就诊的 2 型糖尿病患者中血脂异常的患病率。
在获得机构审查委员会的伦理批准后，于 2020 年 2 月 18 日至 2020 年 8 月 18 日在一家三级保健中心对 2 型糖尿病患者进行了一项描述性横断面研究。使用经过验证和校准的工具分析和记录人口统计学和血液样本。采用便利抽样技术。点估计值在 95%置信区间内计算。
在 390 名 2 型糖尿病患者中，有 343 名（87.95%）（84.72-91.18，95%置信区间）患有血脂异常。最常见的血脂异常是低高密度脂蛋白胆固醇血症，为 85 例（24.78%），其次是混合性血脂异常，为 305 例（88.92%）。
与在类似环境中进行的研究相比，2 型糖尿病患者血脂异常的患病率较高。我们建议定期检查血糖和血脂水平，以便早期发现血脂异常，并对其进行医学监测，以减少心血管疾病的不良并发症。
心血管疾病；血脂异常；患病率；2 型糖尿病
