某三级医疗中心内科缺血性脑卒中患者的血脂异常：一项描述性横断面研究。

Dyslipidemia among Patients with Ischemic Stroke in the Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study.

机构信息

Department of Internal Medicine, National Academy of Medical Science, Bir Hospital, Mahabouddha, Kathmandu, Nepal.

Department of Biochemistry, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2022 Jun 1;60(250):511-516. doi: 10.31729/jnma.7491.

DOI:10.31729/jnma.7491

PMID:35690976

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9275451/

Abstract

INTRODUCTION

Stroke is a leading cause of morbidity and disability in Asian population. Dyslipidemia is considered a major risk factor for various cardiovascular diseases. The study aimed to find the prevalence of dyslipidemia among patients with ischemic stroke in the Department of Medicine of a tertiary care centre.

METHODS

This is a descriptive cross-sectional study conducted among 150 diagnosed cases of ischemic stroke admitted in the Department of Medicine from 1st October, 2020 to 1st October, 2021. The ethical clearance was taken from the Institutional Review Committee (Reference number: 358/2077/78). Fasting blood samples were collected from the patients, serum lipids were measured and atherogenic indices of plasma were calculated. Demographic, anthropometric and cardiovascular risk factors related data were collected. Data were entered in Microsoft Excel 2010 and analysis was using the Statistical Package for the Social Sciences version 22.0. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data, and mean and standard deviation for continuous data.

RESULTS

The prevalence of dyslipidemia among the ischemic stroke patients was 120 (80.00%) (73.60-86.40 at 95% Confidence Interval). High total cholesterol was found in 64 (53.33%) patients, high triglycerides in 70 (58.33%), high low-density lipoprotein cholesterol in 54 (45.00%) and low high-density lipoprotein cholesterol in 51 (42.50%) patients.

CONCLUSIONS

The prevalence of dyslipidemia among ischemic stroke patients was higher than the studies done in similar settings.

KEYWORDS

dyslipidemia; ischemic stroke; lipid; prevalence.

摘要

简介

卒中是亚洲人群发病率和致残率的主要原因之一。血脂异常被认为是各种心血管疾病的主要危险因素。本研究旨在探讨某三级医疗中心内科收治的缺血性卒中患者血脂异常的患病率。

方法

这是一项在 2020 年 10 月 1 日至 2021 年 10 月 1 日期间入住内科的 150 例确诊缺血性卒中患者中进行的描述性横断面研究。本研究已获得机构审查委员会的伦理批准（注册号：358/2077/78）。从患者中采集空腹血样，检测血清脂质，并计算血浆致动脉粥样硬化指数。收集人口统计学、人体测量学和心血管危险因素相关数据。数据输入 Microsoft Excel 2010 中，使用统计软件包（版本 22.0）进行分析。计算 95%置信区间的点估计值，同时对二分类数据进行频率和比例分析，对连续数据进行均值和标准差分析。