工业氢氟酸暴露的尿氟监测。

Urinary fluoride monitoring of industrial hydrofluoric acid exposure.

作者信息

Kono K, Yoshida Y, Yamagata H, Watanabe M, Shibuya Y, Doi K

出版信息

Environ Res. 1987 Apr;42(2):415-20. doi: 10.1016/s0013-9351(87)80208-6.

Abstract

Preworkshift and postworkshift urinary fluoride concentrations were measured in 142 hydrofluoric acid (HF) workers and 82 unexposed workers aged 18 to 59. Postshift urinary fluoride concentration in HF workers was significantly higher than that in preshift or control workers. A linear relationship was observed between the mean values in urinary fluoride concentration and the HF concentration in the air. The mean urinary fluoride concentration of 4 ppm and its lower fiducial limit (95%, P = 0.05) of 2 ppm (specific gravity 1.024) were estimated corresponding to the atmospheric HF concentration of 3 ppm, which is the maximal allowable concentration recommended by the Japanese Association of Industrial Health and also the threshold limit value suggested by the American Conference of Governmental Industrial Hygienists. The results suggest that exposure to HF can be monitored by determining the urinary fluoride concentration.

摘要

对142名年龄在18至59岁的氢氟酸（HF）工人和82名未接触者进行了班前和班后尿氟浓度测量。HF工人的班后尿氟浓度显著高于班前或对照组工人。观察到尿氟浓度平均值与空气中HF浓度之间存在线性关系。估计大气HF浓度为3 ppm时，尿氟平均浓度为4 ppm，其较低置信限（95%，P = 0.05）为2 ppm（比重1.024），这是日本产业卫生协会推荐的最大允许浓度，也是美国政府工业卫生学家会议建议的阈限值。结果表明，通过测定尿氟浓度可以监测HF暴露情况。