Department of Operative Dentistry and Periodontology, Centre of Dental Medicine, University of Cologne, Cologne, Germany.
Faculty of Medicine and University Hospital Cologne, Institute of Medical Statistics and Computational Biology, University of Cologne, Cologne, Germany.
Eur J Oral Sci. 2022 Aug;130(4):e12880. doi: 10.1111/eos.12880. Epub 2022 Jun 12.
This study aimed to establish whether the modified Schirmer test could serve as a diagnostic tool for dry mouth, that is, whether it could reliably measure salivary film at selected locations within the oral cavity, and to identify levels of sensitivity/specificity and determine reference values. Therefore, a cross-sectional study (N = 120, mean age 63.5 [SD 13.9] years) was performed. The test was used at five locations (hard palate; buccal mucosa in molar region at 4 mm above occlusal plane; anterior tongue; lower lip; mouth floor), and results were recorded after 1, 2 and 3 min. A statistically significant discriminatory ability of the Schirmer test for the unstimulated salivary flow rates could be shown for the palate (at 3 min), buccal mucosa (at 1 min), mouth floor (at 1 min), and tongue (at 2 and 3 min) (areas under the curve 0.64-0.68), with individual sensitivity/specificity values depending on test location/time points. Thus, the modified Schirmer test has potential to become a simple and reproducible instrument for the detection of dry mouth based on low unstimulated salivary flow rates in dentistry and especially outreach care. Care must be taken concerning intraoral test location and measurement time.
本研究旨在确定改良 Schirmer 试验是否可作为口干的诊断工具，即它是否能可靠地测量口腔内选定部位的唾液膜，并确定其敏感性/特异性的水平和参考值。因此，进行了一项横断面研究（N=120，平均年龄 63.5[SD 13.9]岁）。该试验在五个部位（硬腭；磨牙区颊粘膜距咬合平面 4mm 处；前舌；下唇；口底）进行，记录 1、2 和 3 分钟后的结果。改良 Schirmer 试验对未刺激唾液流率有显著的区分能力，可用于评估硬腭（3 分钟时）、颊粘膜（1 分钟时）、口底（1 分钟时）和舌（2 分钟和 3 分钟时）（曲线下面积为 0.64-0.68），测试部位/时间点不同，敏感性/特异性值也不同。因此，改良 Schirmer 试验具有成为基于口腔内低未刺激唾液流率进行口腔检查和口腔护理的简单且可重复的口干检测工具的潜力。需要注意口腔内测试部位和测量时间。
