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童年不良经历与产后抑郁症之间的关联

The Association Between Adverse Childhood Experiences and Postpartum Depression.

作者信息

Prentice Danielle M, Otaibi Banan W, Stetter Christy, Kunselman Allen R, Ural Serdar H

机构信息

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, United States.

Penn State College of Medicine, Hershey, PA, United States.

出版信息

Front Glob Womens Health. 2022 May 26;3:898765. doi: 10.3389/fgwh.2022.898765. eCollection 2022.

Abstract

OBJECTIVE

Adverse childhood experiences (ACEs) are linked to worsening overall health outcomes and psychological diagnoses. Routine screening, particularly in patients with postpartum depression (PPD), would identify patients who could benefit from interventions to prevent the perpetuation of ACEs and establish a system of preventative care to mitigate the risks of adverse health outcomes associated with high ACE scores. The purpose of this study is to explore the link between ACEs and PPD to advocate for the use of the ACE questionnaire as a routine screening tool in all pregnant patients diagnosed with PPD. We hypothesize that a cohort of patients with PPD will be more likely to have high-risk ACE scores than the general female population.

STUDY DESIGN

Our IRB approved, retrospective cohort study identified all patients diagnosed with PPD at an academic medical center between January 2015 and December 2019. The subjects were identified using retrospective chart review. Subjects were recruited via telephone and asked to complete an ACE questionnaire. Questionnaires were sent via RedCap. ACE scores were calculated, categorized as 0, 1, 2, 3, or 4 or more ACEs, and compared to the prevalence in the original Kaiser-CDC ACE study female cohort using a chi-square goodness-of-fit test.

RESULTS

There were 132/251 surveys completed (53% response rate). In our PPD population, 19.3% had 0 ACEs, 17.0% had 1 ACE, 13.1% had 2 ACEs, 16.5% had 3 ACEs, and 34.1% had 4 or more ACEs. These percentages were significantly different from the Kaiser-CDC ACE Study percentages of 34.5, 24.5, 15.5, 10.3, and 15.2%, respectively ( < 0.001).

CONCLUSION

Our unique study showed that women with PPD are more likely to have high-risk ACE scores than the general female population. This finding has important implications in regards to counseling, intervening to prevent perpetual ACEs, and establishing important provider-patient relationships for life-long preventative care.Non-gendered language is used when possible throughout. However, the wording from studies cited in this paper was preserved.

摘要

目的

儿童期不良经历(ACEs)与整体健康状况恶化及心理诊断相关。常规筛查,尤其是对产后抑郁症(PPD)患者进行筛查,能够识别出可从干预措施中获益的患者,以防止ACEs持续存在,并建立预防性护理体系,降低与高ACE分数相关的不良健康结局风险。本研究的目的是探讨ACEs与PPD之间的联系,倡导将ACE问卷作为所有被诊断为PPD的孕妇的常规筛查工具。我们假设,一组PPD患者比一般女性人群更有可能有高风险的ACE分数。

研究设计

我们的研究经机构审查委员会(IRB)批准,为回顾性队列研究,识别了2015年1月至2019年12月期间在一家学术医疗中心被诊断为PPD的所有患者。通过回顾病历确定研究对象。通过电话招募受试者,并要求他们完成一份ACE问卷。问卷通过RedCap发送。计算ACE分数,分为0、1、2、3或4个及以上ACEs,并使用卡方拟合优度检验与最初的凯泽 - 疾病预防控制中心(Kaiser - CDC)ACE研究女性队列中的患病率进行比较。

结果

共完成了132/251份调查(回复率为53%)。在我们的PPD人群中,19.3%的人有0个ACEs,17.0%的人有1个ACE,13.1%的人有2个ACE,16.5%的人有3个ACE,34.1%的人有4个及以上ACEs。这些百分比与凯泽 - CDC ACE研究中的百分比(分别为34.5%、24.5%、15.5%、10.3%和15.2%)有显著差异(<0.001)。

结论

我们独特的研究表明,患有PPD的女性比一般女性人群更有可能有高风险的ACE分数。这一发现对于咨询、干预以防止ACEs持续存在以及建立重要的医患关系以提供终身预防性护理具有重要意义。本文尽可能使用无性别倾向的语言。然而,保留了本文引用研究中的措辞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a615/9183059/55d69defb06a/fgwh-03-898765-g0001.jpg

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