Research Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, WC1E 6BT, London, United Kingdom.
Research Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, WC1E 6BT, London, United Kingdom.
Child Abuse Negl. 2021 Feb;112:104890. doi: 10.1016/j.chiabu.2020.104890. Epub 2021 Jan 13.
Adverse childhood experiences (ACEs) predict poorer mental health across the life course but most of the extant research has employed ACE scores or individual adversities using retrospective data.
To study the impact of ACEs on later mental health using not only ACEs scores and individual ACEs, but also latent class analysis (LCA), which respects the clustering of adversities.
8823 members from the UK Millennium Cohort Study.
We investigated the impact of prospectively reported ACEs on mental health trajectories derived using the Strengths and Difficulties Questionnaire at age 3, 5, 7, 11 and 14. Associations between LCA-derived ACE clusters, ACE scores, individual ACEs and mental health trajectories were tested using linear mixed effects models.
With statistical significance set at 5% level, ACE scores showed a graded association with internalizing (ACE score of 1: β = 0.057; ACE score of 2: β = 0.108; ACE score of 3: β = 0.202), externalizing (ACE score of 1: β = 0.142; ACE score of 2: β = 0.299; ACE score of 3: β = 0.415) and prosocial behaviors (ACE score of 1: β=-0.019; ACE score of 2: β=-0.042; ACE score of 3: β=-0.059). Harsh parenting and physical punishment were particularly strongly associated with externalizing (β = 0.270 and β = 0.256) and negatively associated with prosocial behaviors (β=-0.046 and β=-0.058). Parental discord and parental depression showed the strongest associations with internalizing problems (β = 0.125 and β = 0.113). LCA did not discriminate ACE clusters in this dataset.
ACEs have an important impact on mental health from childhood to adolescence. ACEs score approach yielded useful results, which were further enhanced by exploring individual ACEs.
不良的童年经历（ACEs）会预测整个生命周期内较差的心理健康状况，但大多数现有研究都使用回溯性数据的 ACE 评分或个别 ACE 来进行预测。
使用 ACE 评分和个体 ACE 以外的方法，如潜在类别分析（LCA），来研究 ACE 对后期心理健康的影响，因为后者更尊重逆境的聚类性。
来自英国千禧年队列研究的 8823 名成员。
我们研究了前瞻性报告的 ACEs 对使用 Strengths and Difficulties Questionnaire 在 3、5、7、11 和 14 岁时得出的心理健康轨迹的影响。使用线性混合效应模型测试 LCA 衍生 ACE 聚类、ACE 评分、个体 ACEs 与心理健康轨迹之间的关联。
将统计学显著性设置为 5%水平，ACE 评分与内化问题（ACE 评分 1：β=0.057；ACE 评分 2：β=0.108；ACE 评分 3：β=0.202）、外化问题（ACE 评分 1：β=0.142；ACE 评分 2：β=0.299；ACE 评分 3：β=0.415）和亲社会行为（ACE 评分 1：β=-0.019；ACE 评分 2：β=-0.042；ACE 评分 3：β=-0.059）呈梯度相关。严厉的养育和体罚与外化问题特别强烈相关（β=0.270 和 β=0.256），与亲社会行为呈负相关（β=-0.046 和 β=-0.058）。父母不和和父母抑郁与内化问题的相关性最强（β=0.125 和 β=0.113）。在这个数据集，LCA 无法区分 ACE 聚类。
ACEs 对儿童期到青春期的心理健康有重要影响。ACE 评分方法得出了有用的结果，通过探索个体 ACE 进一步增强了这些结果。
