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ALPK1:一种细菌ADP-庚糖的模式识别受体。

ALPK1: a pattern recognition receptor for bacterial ADP-heptose.

作者信息

Cong Yingzi

机构信息

Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, TX, USA.

Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.

出版信息

Precis Clin Med. 2018 Sep;1(2):57-59. doi: 10.1093/pcmedi/pby012. Epub 2018 Sep 22.

Abstract

A commentary on "Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose".

摘要

关于“α-激酶1是细菌ADP-庚糖的胞质内先天性免疫受体”的评论

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Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose.
Nature. 2018 Sep;561(7721):122-126. doi: 10.1038/s41586-018-0433-3. Epub 2018 Aug 15.
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Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway.
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ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria.
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Pattern recognition receptors and inflammation.
Cell. 2010 Mar 19;140(6):805-20. doi: 10.1016/j.cell.2010.01.022.
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NOD-like receptors: role in innate immunity and inflammatory disease.
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