一种基于苯硼酸和基于BODIPY的疏水性探针的用于果糖检测的选择性混合荧光传感器。
A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based hydrophobicity probe.
作者信息
Kashiwazaki Gengo, Watanabe Ryo, Nishikawa Akihiro, Kawamura Koyori, Kitayama Takashi, Hibi Takao
机构信息
Major in Advanced Bioscience, Graduate School of Agriculture, Kindai University 3327-204, Nakamachi Nara Nara 631-8505 Japan
Department of Bioscience and Biotechnology, Faculty of Bioscience and Biotechnology, Fukui Prefectural University 4-1-1 Matsuoka-Kenjojima, Eiheiji Fukui 910-1195 Japan
出版信息
RSC Adv. 2022 May 18;12(24):15083-15090. doi: 10.1039/d2ra01569b. eCollection 2022 May 17.
Fructose is widely used in the food industry. However, it may be involved in diseases by generating harmful advanced glycation end-products. We have designed and synthesized a novel fluorescent probe for fructose detection by combining a phenylboronic acid group with a BODIPY-based hydrophobicity probe. This probe showed a linear fluorescence response to d-fructose concentration in the range of 100-1000 μM, with a detection limit of 32 μM, which is advantageous for the simple and sensitive determination of fructose.
果糖在食品工业中被广泛使用。然而，它可能通过产生有害的晚期糖基化终产物而与疾病有关。我们通过将苯硼酸基团与基于BODIPY的疏水性探针相结合，设计并合成了一种用于果糖检测的新型荧光探针。该探针对100 - 1000 μM范围内的d-果糖浓度呈现线性荧光响应，检测限为32 μM，这有利于果糖的简单灵敏测定。
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