Basodan Nojood, Al Mehmadi Abdulaziz E, Al Mehmadi Abdullah E, Aldawood Sulaiman M, Hawsawi Ashraf, Fatini Fahad, Mulla Ziyad M, Nawwab Waleed, Alshareef Ammar, Almhmadi Amir H, Ahmed Amin, Bokhari Abdulwahab, Alzahrani Abdulaziz G
Emergency Department, King Faisal Hospital, Makkah, SAU.
Neurosurgery Department, King Faisal Hospital, Makkah, SAU.
Cureus. 2022 Dec 3;14(12):e32158. doi: 10.7759/cureus.32158. eCollection 2022 Dec.
The incidence rates of sepsis and septic shock as a complication have become more common over the past several decades. With this increase, sepsis remains the most common cause of intensive care unit (ICU) admissions and one of the most mortality factors, with a huge burden on healthcare facilities. Septic shock has devastating consequences on patients' lives, including organ failures and other long-term complications. Due to its dynamic clinical presentations, guidelines and tools have been established to improve the diagnosis and management effectively. However, there is still a need for evidence-based standardized procedures for the diagnosis, treatment, and follow-up of sepsis and septic shock patients due to the inconsistency of current guidelines and studies contrasting with each other. The standardization would help physicians better manage sepsis, minimize complications and reduce mortality. Septic shock is usually challenging to manage due to its variety of clinical characteristics and physiologic dynamics, affecting the outcomes. Therefore, this review presented the available data in the literature on septic shock diagnosis, management, and prognosis to have an overview of the updated best practice approach to septic shock.
在过去几十年中,作为一种并发症的脓毒症和脓毒性休克的发病率变得更加常见。随着这种增加,脓毒症仍然是重症监护病房(ICU)收治的最常见原因,也是最致命的因素之一,给医疗设施带来了巨大负担。脓毒性休克对患者的生命有毁灭性影响,包括器官衰竭和其他长期并发症。由于其动态的临床表现,已经建立了指南和工具来有效改善诊断和管理。然而,由于当前指南和相互矛盾的研究存在不一致性,对于脓毒症和脓毒性休克患者的诊断、治疗和随访仍需要基于证据的标准化程序。标准化将有助于医生更好地管理脓毒症,将并发症降至最低并降低死亡率。由于其多样的临床特征和生理动态,脓毒性休克的管理通常具有挑战性,会影响治疗结果。因此,本综述展示了文献中关于脓毒性休克诊断、管理和预后的现有数据,以概述脓毒性休克最新的最佳实践方法。