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三种不同再矿化剂对乳牙人工侵蚀性龋损的影响。

Effect of three different remineralizing agents on artificial erosive lesions of primary teeth.

机构信息

Faculty of Dentistry, Department of Pedodontics, Istanbul Medipol University, Istanbul, Turkey.

Faculty of Dentistry, Department of Pedodontics, Istanbul University, Istanbul, Turkey.

出版信息

Aust Dent J. 2022 Sep;67(3):271-280. doi: 10.1111/adj.12922. Epub 2022 Jun 27.

Abstract

BACKGROUND

This study aimed to investigate the efficacy of three remineralizing agents on dental erosion in primary teeth.

METHODS

Forty primary molars were randomly divided into four groups (n = 10 each): self-assembling peptide (P ), casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP), sodium fluoride (NaF) and artificial saliva (AS; control). The erosion-like formation was created by immersing the samples in citric acid (4 × 2 min, pH 2.3) and AS (4 × 2 h, pH 7). The eroded samples were then treated with remineralizing agents and subjected to further erosion consisting of 15 cycles (3x/8-h interval) of immersion in citric acid and AS for 6 s each. Alterations in the mineral content and morphology of the samples were quantified using a microhardness tester and atomic force microscope.

RESULTS

All agents had a significant remineralization effect on eroded primary tooth enamel. After further erosive challenge, enamel loss in the CPP-ACFP group was found to be significantly lower than in all other groups, and no significant difference was found between the P and NaF groups.

CONCLUSIONS

This study showed that all tested materials had remineralization ability, and CPP-ACFP had a superior effect in inhibiting enamel loss due to dental erosion in primary teeth. © 2022 Australian Dental Association.

摘要

背景

本研究旨在探讨三种再矿化剂对乳牙酸蚀的疗效。

方法

将 40 颗乳磨牙随机分为四组(每组 10 颗):自组装肽(P)、酪蛋白磷酸肽-无定形氟化钙磷(CPP-ACFP)、氟化钠(NaF)和人工唾液(AS;对照组)。通过将样本浸泡在柠檬酸(4×2 分钟,pH2.3)和 AS(4×2 小时,pH7)中,形成类似酸蚀的形成。然后用再矿化剂处理受侵蚀的样本,并进行进一步的侵蚀,包括柠檬酸和 AS 各浸泡 15 个循环(3x/8 小时间隔),每次 6 秒。使用显微硬度计和原子力显微镜定量测量样本的矿物质含量和形态变化。

结果

所有试剂对受侵蚀的乳牙釉质均有显著的再矿化作用。在进一步的侵蚀性挑战后,发现 CPP-ACFP 组的釉质损失明显低于其他所有组,而 P 和 NaF 组之间没有显著差异。

结论

本研究表明,所有测试材料均具有再矿化能力,CPP-ACFP 对抑制乳牙酸蚀引起的釉质丧失具有更好的效果。©2022 澳大利亚牙科协会。

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