Department of Pediatric Dentistry, Faculty of Dentistry, Trakya University, 22030, Edirne, Turkey.
Department of Prosthodontics, Faculty of Dentistry, Trakya University, Edirne, Turkey.
Eur Arch Paediatr Dent. 2023 Oct;24(5):651-659. doi: 10.1007/s40368-023-00834-x. Epub 2023 Aug 30.
This study aimed to evaluate and compare the protective effect of fluoride varnish (Enamelast™, Ultradent Inc., Cologne, Germany), casein phosphopeptide-amorphous calcium phosphate fluoride/CPP-ACPF (MI Paste Plus, GC Corp., Tokyo, Japan) and self-assembling P peptide (Curodont™ Protect, Credentis AG, Windisch, Switzerland), against acidic erosion of primary teeth.
Forty primary anterior teeth were randomly assigned to four groups (n = 10): group 1: control, group 2: fluoride varnish, group 3: CPP-ACPF and group 4: self-assembling P peptide. After applying remineralising agents, except for the control group, all specimens underwent an erosive challenge of carbonated soft drink and artificial saliva for 15 cycles of 6 s each at 6-h intervals for a day. Groups were compared in terms of surface microhardness, roughness readings, and surface scanning with an extra-oral scanner (D800; 3Shape A/S) before and after the erosive process.
All experimental groups showed superior results than the control group regarding microhardness, surface roughness, and substance loss. The fluoride varnish group showed significantly favourable results in microhardness change. There was no significant difference between the experimental groups regarding surface roughness and enamel loss measurements.
5% NaF fluoride varnish, CPP-ACPF and self-assembling P peptide protect the enamel of primary teeth against erosion compared to artificial saliva alone.
本研究旨在评估和比较氟化物漆(Enamelast™,Ultradent Inc.,德国科隆)、酪蛋白磷酸肽-无定形磷酸钙氟化物/CPP-ACPF(MI Paste Plus,GC 公司,日本东京)和自组装 P 肽(Curodont™ Protect,Credentis AG,温迪士,瑞士)对乳牙酸性侵蚀的保护作用。
40 颗前乳牙被随机分为四组(n = 10):第 1 组:对照组,第 2 组:氟化物漆,第 3 组:CPP-ACPF,第 4 组:自组装 P 肽。除对照组外,所有标本在应用再矿化剂后,均在碳酸软饮料和人工唾液中进行 15 个 6 秒循环的侵蚀挑战,每隔 6 小时进行一次,持续一天。在侵蚀过程前后,使用口腔外扫描仪(D800;3Shape A/S)对各组进行表面显微硬度、粗糙度读数和表面扫描比较。
所有实验组的显微硬度、表面粗糙度和物质损失均优于对照组。氟化物漆组在显微硬度变化方面表现出明显的优势。实验组之间在表面粗糙度和釉质损失测量方面没有显著差异。
与单独使用人工唾液相比,5%NaF 氟化物漆、CPP-ACPF 和自组装 P 肽可保护乳牙牙釉质免受侵蚀。