Key Laboratory of Edible Fungi Resources and Utilization, Ministry of Agriculture and Rural Affairs, Jilin Agricultural University, Changchun, Jilin, 130118, China; Department of Agricultural Chemistry, Faculty of Agriculture, Minia University, Minia 6111.
Engineering Research Center of the Chinese Ministry of Education for Edible and Medicinal Fungi and Jilin Province Medical Fungus Resources and Its Development and Utilization Key Research Laboratory, Jilin Agricultural University, Changchun, Jilin 130118, P.R. China.
Int J Med Mushrooms. 2022;24(6):19-33. doi: 10.1615/IntJMedMushrooms.2022043854.
The medicinal mushroom Leucocalocybe mongolica has received much attention from biologists since the end of the last century due to its rich bioactive compounds and high efficiency against a wide range of chronic diseases. Many years ago, L. mongolica was used in traditional Chinese medicine. About 100 chemical components have been isolated and/or identified in L. mongolica, especially fruiting bodies. This mushroom is rich in polysaccharides, sterols, lectins, laccase, amino acids, and volatile compounds. The bioactive compounds from L. mongolica possess significant pharmacological activities such as antitumor, antiproliferative, antidiabetic, and hypotensive effects. However, some bioactive characteristics of this mushroom still need further investigation to elucidate the multiple biological and pharmacological uses. Furthermore, L. mongolica requires scientific proof regarding its use to enhance milk production and mammary gland differentiation. In this review, we summarize the pharmacological and therapeutic properties of L. mongolica and provide suggestions for future research on this medicinal mushroom.
药用蘑菇蒙古口蘑自上世纪末以来因其丰富的生物活性化合物和对多种慢性疾病的高效性而受到生物学家的广泛关注。许多年前，蒙古口蘑就被应用于中药。在蒙古口蘑中已经分离和/或鉴定出约 100 种化学成分，尤其是子实体。这种蘑菇富含多糖、固醇、凝集素、漆酶、氨基酸和挥发性化合物。蒙古口蘑中的生物活性化合物具有显著的药理活性，如抗肿瘤、抗增殖、降血糖和降血压作用。然而，这种蘑菇的一些生物活性特征仍需要进一步研究，以阐明其多种生物学和药理学用途。此外，蒙古口蘑的催乳和乳腺分化作用需要科学证据支持。在这篇综述中，我们总结了蒙古口蘑的药理和治疗特性，并为该药用蘑菇的进一步研究提供了建议。
