Department of Clinical Surgery, Diagnostics and Pediatrics, Fondazione IRCCS Policlinico San Matteo, Viale Brambilla 74, 27100, Pavia, Italy.
PhotoGreen Lab, Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100, Pavia, Italy.
ChemSusChem. 2022 Sep 7;15(17):e202200898. doi: 10.1002/cssc.202200898. Epub 2022 Jul 8.
The valorization of alkenoic acids possibly deriving from biomass (fumaric and citraconic acids) was carried out through conversion in important building blocks, such as γ-keto acids and succinic acid derivatives. The functionalization was carried out by addition onto the C=C double bond of radicals generated under photocatalyzed conditions from suitable hydrogen donors (mainly aldehydes) and by adopting a decatungstate salt as the photocatalyst. Syntheses were performed under batch (in a glass vessel) and flow (by using 3D-printed reactors) conditions. The design of the latter reactors allowed for an improved yield and productivity.
通过将可能来自生物质的烯酸（富马酸和柠康酸）转化为重要的构建块（如γ-酮酸和琥珀酸衍生物），实现了其增值。该功能化是通过在光催化条件下由合适的氢供体（主要是醛）生成的自由基的 C=C 双键加成来实现的，并采用多钨酸盐盐作为光催化剂。合成在分批（在玻璃容器中）和流动（使用 3D 打印反应器）条件下进行。后者反应器的设计提高了收率和生产效率。
