Bellantuono C, Fiorio R, Williams P, Martini N, Bozzini L
Fam Pract. 1987 Mar;4(1):41-9. doi: 10.1093/fampra/4.1.41.
A psychotropic drug monitoring study in general practice was carried out in 1983 and 1984 using a computerized drug information system. The prescription data analysed in the study came from 68 general practitioners operating in south Verona and have been collected by 14 community pharmacies located in the same area. Benzodiazepine hypnotics were the most commonly prescribed drugs, followed by antidepressants and neuroleptics both in 1983 and in 1984. The distribution of the general practitioners in terms of low, medium and high prescribers was examined by analysing the rates of prescriptions per registered patient. The rates were obtained for the total number of prescriptions and also for each of the three different classes of psychotropic drug. The proportion of low and high prescribers decreased from 1983 to 1984 (18.3 versus 11.7 and 26.7 versus 16.7 for low and high prescribers respectively); this change was mainly due to the reduction in benzodiazepine prescriptions. No significant correlation was found between the rates of psychotropic drug prescriptions and list size. The monthly variation in prescription of the three drug classes followed a similar pattern during the two years; the fluctuations were clearly cyclical, more definitely in 1984 than in 1983 where the most relevant feature was the summer trough.
1983年和1984年，利用计算机化的药物信息系统在普通医疗中开展了一项精神药物监测研究。该研究中分析的处方数据来自维罗纳南部的68名全科医生，并由同一地区的14家社区药房收集。苯二氮䓬类催眠药是最常开具的药物，其次是抗抑郁药和抗精神病药，在1983年和1984年均如此。通过分析每位注册患者的处方率，研究了全科医生在低、中、高处方者方面的分布情况。该比率是针对处方总数以及三类不同精神药物中的每一类获得的。从1983年到1984年，低处方者和高处方者的比例有所下降（低处方者分别为18.3%对11.7%，高处方者分别为26.7%对16.7%）；这种变化主要是由于苯二氮䓬类处方的减少。未发现精神药物处方率与名单规模之间存在显著相关性。在这两年中，三类药物处方的月度变化遵循相似模式；波动明显呈周期性，1984年比1983年更明显，1983年最相关的特征是夏季低谷。
