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微波技术在皮肤科的潜在应用。

Potential use of microwave technology in dermatology.

机构信息

Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Mediprobe Research Inc, London, Ontario, Canada.

出版信息

J Dermatolog Treat. 2022 Nov;33(7):2899-2910. doi: 10.1080/09546634.2022.2089333. Epub 2022 Jun 20.

Abstract

BACKGROUND

Microwaves are used in medicine for diagnostics, and treatment of cancer. Recently, novel microwave devices (Swift, Emblation Ltd, UK and miraDry, Miramar Labs Inc., CA) have been cleared by the FDA and Health Canada for various dermatological conditions.

OBJECTIVE AND METHODS

To review the dermatological use of microwave-based treatments (plantar warts, corns, actinic keratosis, dermatophytosis, axillary hyperhidrosis, osmidrosis, and hidradenitis suppurativa). Clinical trials, case reports, or studies for each condition are summarized.

RESULTS AND CONCLUSION

Microwaves are a promising alternative therapy for cutaneous warts, actinic keratosis, axillary hyperhidrosis, and osmidrosis, with favorable safety profiles. However, patients with hidradenitis suppurativa have had negative clinical outcomes. Limited treatment of corns showed good pain reduction but did not resolve hyperkeratosis. A preliminary study indicated that microwave treatment inhibits the growth of . We present the first case of toenail onychomycosis successfully treated with microwaves. Despite the advancements in the use of microwaves, the mechanism of action in non-ablative treatment is not well understood; further research is needed. More high-quality randomized clinical trials with larger groups and long follow-up periods are also required to evaluate the clinical benefits and possible adverse effects of microwaves in treating dermatological conditions.

摘要

背景

微波在医学诊断和癌症治疗中得到应用。最近,新型微波设备(Swift、Emblation Ltd,英国和 miraDry、Miramar Labs Inc.,美国)已获得美国 FDA 和加拿大卫生部批准,可用于治疗各种皮肤科疾病。

目的和方法

综述微波治疗(足底疣、鸡眼、光化性角化病、皮肤癣菌病、腋窝多汗症、臭汗症和化脓性汗腺炎)在皮肤科的应用。对每种疾病的临床试验、病例报告或研究进行总结。

结果和结论

微波治疗皮肤疣、光化性角化病、腋窝多汗症和臭汗症具有良好的安全性,是一种有前途的替代疗法。然而,化脓性汗腺炎患者的临床疗效不佳。对鸡眼的有限治疗显示出良好的疼痛缓解,但不能解决过度角化。初步研究表明,微波治疗可抑制 的生长。我们报告了首例微波治疗成功的趾甲甲真菌病病例。尽管微波的应用有了进展,但非消融性治疗的作用机制尚未完全清楚;需要进一步研究。还需要更多高质量的随机临床试验,纳入更大的人群并进行更长时间的随访,以评估微波治疗皮肤科疾病的临床获益和可能的不良反应。

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