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与HIV继发疾病相关的病理性骨折后的并发症及手术治疗。病例报告。

Complications and surgical treatment after pathological fracture associated to HIV secondary disease. A case report.

作者信息

Fuentes-Sánchez Jorge, Gómez-Barrena Enrique

机构信息

Orthopaedic Surgery and Traumatology Department, Hospital Universitario La Paz, P° Castellana 261, 28046 Madrid, Spain.

Orthopaedic Surgery and Traumatology Department, Hospital Universitario La Paz, Universidad Autónoma de Madrid, P° Castellana 261, 28046 Madrid, Spain.

出版信息

J Surg Case Rep. 2022 Jun 10;2022(6):rjac223. doi: 10.1093/jscr/rjac223. eCollection 2022 Jun.

Abstract

Due to advances in retroviral treatment, human immunodeficiency virus (HIV)-related disease may become chronic and the patient survival has substantially increased. Osteoarticular disease in those patients include multifocal osteonecrosis and its complications. Pain and functional limitation may be due to these complications, frequently underdiagnosed, including pathological fractures. Its prompt management may require a different approach than osteosynthesis. We present a long-term chronic HIV patient with severe pain and limitation. A tibial plateau pathological fracture associated to multifocal osteonecrosis was identified and treated with osteonecrosis debridement and total knee arthroplasty (TKA). Acute periprosthetic joint infection developed and required debridement, antibiotic and implant retention. The contralateral knee, also with multiple osteonecrosis foci, was managed with early TKA. We highlight the importance of timely surgical reconstruction to avoid serious limitation and complications.

摘要

由于逆转录病毒治疗的进展,人类免疫缺陷病毒(HIV)相关疾病可能会变为慢性,患者生存率显著提高。这些患者的骨关节疾病包括多灶性骨坏死及其并发症。疼痛和功能受限可能归因于这些并发症,其中包括经常未被诊断出的病理性骨折。其及时处理可能需要与骨固定术不同的方法。我们介绍了一名长期患有慢性HIV且伴有严重疼痛和功能受限的患者。诊断出与多灶性骨坏死相关的胫骨平台病理性骨折,并采用骨坏死清创术和全膝关节置换术(TKA)进行治疗。发生了急性假体周围关节感染,需要进行清创、使用抗生素并保留植入物。对侧膝关节也有多个骨坏死病灶,通过早期TKA进行处理。我们强调及时进行手术重建以避免严重功能受限和并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdcd/9187348/de097d3885b7/rjac223f1.jpg

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