1Maine Medical Center Research Institute, Scarborough, Maine, USA.
Eur J Endocrinol. 2022 Jun 29;187(2):R17-R26. doi: 10.1530/EJE-22-0499. Print 2022 Aug 1.
Understanding the development and regulation of marrow adiposity, as well as its impact on skeletal remodeling has been a major challenge for our field and during my career as well. The story behind this unique phenotype and its relationship to bone turnover is highlighted in my own quest to defining the physiology and pathophysiology of marrow adipocytes.
了解骨髓脂肪的发育和调节及其对骨骼重塑的影响一直是我们领域的一个主要挑战,也是我职业生涯中的一个主要挑战。在我定义骨髓脂肪细胞的生理学和病理生理学的探索过程中,突出了这种独特表型及其与骨转换的关系的背后故事。