多能细胞状态和意想不到的命运。
Pluripotent cell states and unexpected fates.
机构信息
The Jackson Laboratory, Bar Harbor, ME 04660, USA.
出版信息
Stem Cell Reports. 2022 Jun 14;17(6):1235-1236. doi: 10.1016/j.stemcr.2022.05.011.
Abstract
Pluripotent stem cells provide a powerful model for the study of human development and its disorders. Recent studies, including two in this issue of Stem Cell Reports, raise important questions concerning the developmental potential of human pluripotent stem cells, and how the behavior of these cells in vitro mirrors normal embryogenesis.
摘要
多能干细胞为研究人类发育及其障碍提供了强大的模型。最近的研究，包括本期《Stem Cell Reports》上的两项研究，提出了关于人类多能干细胞的发育潜力以及这些细胞在体外的行为如何反映正常胚胎发生的重要问题。
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Derivation of functional trophoblast stem cells from primed human pluripotent stem cells.从诱导多能干细胞中衍生功能性滋养层干细胞。
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Amniogenesis occurs in two independent waves in primates.在灵长类动物中，羊膜发生分为两个独立的波。
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