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射频不对称传导神经调节治疗对功能性运动障碍(一种适应性运动行为)的长期疗效

Long-Lasting Efficacy of Radio Electric Asymmetric Conveyer Neuromodulation Treatment on Functional Dysmetria, an Adaptive Motor Behavior.

作者信息

Fontani Vania, Rinaldi Arianna, Rinaldi Chiara, Araldi Laura, Azzarà Alida, Carta Antonio M, Casale Nicoletta, Castagna Alessandro, Del Medico Maurizio, Di Stasio Maurizio, Facchini Marina, Greco Monica, LaMarca Savino, Loro Giovanni, Marrone Anna, Palattella Alessandra, Pellegata Giulio, Ruini Daniele, Schmitt Corrado, Vianini Franco, Maioli Margherita, Ventura Carlo, Caltabiano Franco, Bueno Adriano J, Fugino Matuoka Amélia, Massahiro Nabechima Edison, Bechelli Fabio A, da Silveira Bossi Fabricio, Nitschke Fontana Greice C, Finkielsztejn Jaques, Coelho Pereira José Alfredo, Nunes Callegaro Juarez, Vasconcelos Pinheiro Kleiner, Ferreira Alves Lara R, Kodja Daguer Marcelo, Marins Martins Márcia C, Bezerra Uliana Mauricio, Knop Zisman Nelson, Cezar Schütz Paulo, Fochesato Paulo R, Celso Felipe de Castro Pollyanna, Tanaka Nabechima Rosa M, Randon Roseli B, Rinaldi Salvatore

机构信息

Research, Rinaldi Fontani Foundation, Florence, ITA.

Regenerative Medicine, Rinaldi Fontani Institute, Florence, ITA.

出版信息

Cureus. 2022 Jun 8;14(6):e25768. doi: 10.7759/cureus.25768. eCollection 2022 Jun.

Abstract

Background Fluctuating asymmetry (FA) is widely defined as the deviation from perfect bilateral symmetry and is considered an epigenetic measure of environmental stress. Rinaldi and Fontani hypothesized that the FA morpho-functional changes originate from an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by environmental stress. They called this phenomenon functional dysmetria (FD). On this premise, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction. Aims Previous studies showed that specific REAC neuro postural optimization (NPO) treatment can induce stable FD recovery. This study aimed to verify the duration of the NPO effect in inducing the stable FD recovery over time. Materials and methods Data were retrospectively collected from a population of 29,794 subjects who underwent a specific semiological FD assessment and received the NPO treatment, regardless of the pathology referred. Results The analysis of the data collected by the various participants in the study led us to ascertain the disappearance of FD in 100% of the cases treated, with a stability of the result detected up to 18 years after the single administration of the REAC NPO treatment. Conclusions The REAC NPO neurobiological modulation treatment consisting of a single administration surprisingly maintains a very long efficacy in the correction of FD. This effect can be explained as the long-lasting capacity of the NPO treatment to induce greater functional efficiency of the brain dynamics as proven in previous studies.

摘要

背景 波动不对称性(FA)被广泛定义为与完美双侧对称的偏差,并被视为环境压力的一种表观遗传指标。里纳尔迪和丰塔尼假设,FA的形态功能变化源自由小脑和神经回路功能改变所决定的适应性运动行为,并非由损伤引起,而是由环境压力诱发。他们将这种现象称为功能性辨距不良(FD)。在此前提下,他们开发了无线电电不对称传送器(REAC)技术,这是一种神经调节技术,旨在优化与环境交互相关的最佳神经 - 心理 - 运动策略。目的 先前的研究表明,特定的REAC神经姿势优化(NPO)治疗可诱导FD稳定恢复。本研究旨在验证NPO效应在诱导FD随时间稳定恢复方面的持续时间。材料和方法 回顾性收集了29794名受试者的数据,这些受试者接受了特定的症状学FD评估并接受了NPO治疗,无论其转诊的病理情况如何。结果 对研究中不同参与者收集的数据进行分析后,我们确定在接受治疗的所有病例中FD均消失,在单次给予REAC NPO治疗后长达18年仍检测到结果稳定。结论 令人惊讶的是,单次给予的REAC NPO神经生物学调节治疗在纠正FD方面保持了很长时间的疗效。这种效应可以解释为NPO治疗具有持久能力,能够诱导大脑动力学更高的功能效率,正如先前研究所证明的那样。

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