Bansal Shipra, Connolly Meaghan, Harder Tasha
A.T. Still University, School of Osteopathic Medicine in Arizona, Mesa, Arizona.
Am J Lifestyle Med. 2021 Jun 6;16(3):382-389. doi: 10.1177/15598276211018159. eCollection 2022 May-Jun.
The current study evaluated the impact of a whole-foods, plant-based nutrition intervention on metabolic markers of patients with chronic disease in an underserved community setting. A retrospective analysis of metabolic biomarkers preintervention and postintervention was conducted on 31 patients with metabolic disease who attended an Eating for Life group visit series. Significant decreases were found for body mass index (BMI; -0.66 [-0.91 to -0.40] kg/m), systolic blood pressure (-12 [-19 to -5] mm Hg), total cholesterol (-20 [-29 to -10] mg/dL), low-density lipoprotein (LDL; -11.6 [-17.5 to -5.5] mg/dL), and high-density lipoprotein (HDL; -3.2 [-5.7 to -0.7] mg/dL, all Ps < .01). In participants with clinically abnormal preintervention data, the mean (95% CI) change significantly decreased for overweight (-0.45 [-0.85 to -0.05]) and obese (-0.76 [-1.13 to -0.39]) BMI, systolic blood pressure (-12 [-19 to -5] mm Hg), total cholesterol -22 [-40 to -4] mg/dL), and LDL (-15.6 [-23.8 to -7.4] mg/dL, all Ps ≤ .03). In conclusion, the Eating for Life model showed significant improvement in BMI, diastolic blood pressure, total cholesterol, and LDL in a federally qualified health center population. Group visits advocating for a whole-foods, plant-based diet may be effective in reducing chronic disease burden in underserved communities.
本研究评估了在服务不足的社区环境中，全食物、植物性营养干预对慢性病患者代谢指标的影响。对参加“为生命而食”小组就诊系列的31名代谢疾病患者进行了干预前和干预后代谢生物标志物的回顾性分析。发现体重指数（BMI；-0.66[-0.91至-0.40]kg/m）、收缩压（-12[-19至-5]mmHg）、总胆固醇（-20[-29至-10]mg/dL）、低密度脂蛋白（LDL；-11.6[-17.5至-5.5]mg/dL）和高密度脂蛋白（HDL；-3.2[-5.7至-0.7]mg/dL）均显著下降，所有P值均<0.01。在干预前临床数据异常的参与者中，超重（-0.45[-0.85至-0.05]）和肥胖（-0.76[-1.13至-0.39]）的BMI、收缩压（-12[-19至-5]mmHg）、总胆固醇（-22[-40至-4]mg/dL）和LDL（-15.6[-23.8至-7.4]mg/dL）的平均（95%CI）变化均显著下降，所有P值均≤0.03。总之，“为生命而食”模式在联邦合格健康中心人群中，在BMI、舒张压、总胆固醇和LDL方面显示出显著改善。倡导全食物、植物性饮食的小组就诊可能有助于减轻服务不足社区的慢性病负担。
