Adriaansen F C, Verwoerd-Verhoef H L, Van der Heul R O, Verwoerd C D
Int J Pediatr Otorhinolaryngol. 1986 Dec;12(2):205-15. doi: 10.1016/s0165-5876(86)80076-3.
In young rabbits the histologic features of the growth of the subglottis were studied after an endolaryngeal trauma. This lesion of the larynx leading to a subglottic stenosis, caused specific pathologic changes of the cricoid cartilage and the subepithelial tissues. Activation of chondrocytes resulted in proliferation and regeneration of destructed cartilage. The normal subepithelial structures were replaced by granulation tissue differentiating into a thick fibrous scar and into cartilage. This ectopic cartilage together with the repaired cricoid formed a composite thickened 'ring'-like cartilaginous structure in the adult stage.
在幼兔中，研究了喉内创伤后声门下生长的组织学特征。这种导致声门下狭窄的喉部病变引起了环状软骨和上皮下组织的特定病理变化。软骨细胞的激活导致受损软骨的增殖和再生。正常的上皮下结构被分化为厚纤维瘢痕和软骨的肉芽组织所取代。这种异位软骨与修复后的环状软骨在成年期形成了一个复合增厚的“环状”软骨结构。
