Paul Lizzy Teleboshe, Ergoren Mahmut Cerkez
Department of Medical Biology, Faculty of Medicine, Near East University, Nicosia, Cyprus.
Department of Medical Genetics, Faculty of Medicine, Near East University, Nicosia, Cyprus.
Glob Med Genet. 2022 Feb 25;9(2):72-75. doi: 10.1055/s-0042-1743573. eCollection 2022 Jun.
Prenatal testing provides crucial information about the health status of fetuses as well as recommending better treatment. For the past decades, prenatal testing using chorionic villus sampling and amniocentesis were the two majorly used forms of invasive prenatal diagnostic approaches. However, to facilitate prenatal testing without causing any danger to the fetus, the noninvasive prenatal diagnostic method, which uses circulating cell-free deoxyribonucleic acid (DNA), has become a suitable method of prenatal diagnosis. This review discusses the recent bioinformatics approaches used for analyzing fetal DNA concentration.
产前检测提供有关胎儿健康状况的关键信息，并推荐更好的治疗方法。在过去几十年中，使用绒毛取样和羊膜穿刺术的产前检测是两种主要使用的侵入性产前诊断方法。然而，为了在不危及胎儿的情况下促进产前检测，使用循环游离脱氧核糖核酸（DNA）的非侵入性产前诊断方法已成为一种合适的产前诊断方法。本文综述了最近用于分析胎儿DNA浓度的生物信息学方法。
