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微创远端胰腺切除术中转开腹的危险因素及后果

Risk factors and consequences of conversion in minimally invasive distal pancreatectomy.

作者信息

Jiang Zhiyu, Pan Long, Chen Mingyu, Zhang Bin, Sarun Juengpanich, Fan Sandra, Cai Xiujun

机构信息

Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

J Minim Access Surg. 2022 Jul-Sep;18(3):384-390. doi: 10.4103/jmas.JMAS_4_20.

Abstract

BACKGROUND

Although recent studies have reported potential benefits of laparoscopic approach in distal pancreatectomy, reports of conversion during minimally invasive distal pancreatectomy (MIDP) were limited.

METHODS

This was a retrospective study using data from Sir Run Run Shaw Hospital around May 2013 to December 2018. Outcomes of patients who had conversions during MIDP were compared with patients with successful MIDP and with patients undergoing open distal pancreatectomy (ODP).

RESULTS

Two-hundred and eighty-three cases were included in this study: 225 (79.5%) had MIDP, 30 (10.6%) had conversions and 28 (9.9%) had outpatient department. The risk factors for conversion included large lesion size (heart rates [HR]: 5.632, 95% confidencevinterval [CI]: 1.036-1.450, P = 0.018) and pancreatic cancer (HR: 6.957, 95% CI: 1.359-8.022, P = 0.009). Compared with MIDP, those who required conversion were associated with longer operations (P = 0.003), higher blood loss (P < 0.001) and more severe of the complications (P < 0.001). However, no statistically significant differences were found between the conversion group and ODP.

CONCLUSIONS

Large lesion size and pancreatic cancer were reported to be independent risk factors for conversion during MIDP. As for post-operative outcomes, the outcomes of successfully MIDP were better than those for conversion. However, conversion did not lead to worsening outcomes when compared with ODP.

摘要

背景

尽管近期研究报道了腹腔镜入路在胰体尾切除术中的潜在益处,但关于微创胰体尾切除术(MIDP)中转开腹的报道有限。

方法

这是一项回顾性研究,使用了2013年5月左右至2018年12月邵逸夫医院的数据。将MIDP中转开腹患者的结果与成功完成MIDP的患者以及接受开放性胰体尾切除术(ODP)的患者进行比较。

结果

本研究共纳入283例病例:225例(79.5%)接受了MIDP,30例(10.6%)中转开腹,28例(9.9%)为门诊患者。中转开腹的危险因素包括病变较大(心率[HR]:5.632,95%置信区间[CI]:1.036 - 1.450,P = 0.018)和胰腺癌(HR:6.957,95%CI:1.359 - 8.022,P = 0.009)。与MIDP相比,需要中转开腹的患者手术时间更长(P = 0.003)、失血量更多(P < 0.001)且并发症更严重(P < 0.001)。然而,中转开腹组与ODP组之间未发现统计学上的显著差异。

结论

据报道,病变较大和胰腺癌是MIDP中转开腹的独立危险因素。至于术后结果,成功完成MIDP的患者结果优于中转开腹的患者。然而,与ODP相比,中转开腹并未导致结果恶化。

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