Naismith D J, Rana S K, Emery P W
Hum Nutr Clin Nutr. 1987 Jan;41(1):37-45.
The pattern of excretion of taurine was measured in four omnivore and four vegan/vegetarian women during pregnancy and lactation, and was compared with the changes in urinary excretion of other amino acids, including the precursors of endogenous taurine, observed in ten pregnant omnivores. The loss of taurine in breast milk was also determined in fourteen omnivore and fourteen vegan mothers. In contrast to the rise in excretion of all amino acids during pregnancy, including methionine and cysteine, taurine excretion fell dramatically from week 9 of pregnancy in all subjects, and, in the vegan/vegetarian subjects, fell still further during lactation. Although the concentration of taurine in breast milk was lower in vegan subjects, the mean value fell within the range found in omnivore subjects. Our findings indicate that the suppression of urinary taurine excretion, both during pregnancy and lactation, is a physiological response to reproduction that satisfies the needs of the fetus and the suckling infant for this amino acid. The data also suggest that taurine is stored in the maternal tissues in early pregnancy for later transfer to the fetus.
对四名杂食性和四名纯素食/素食女性在孕期和哺乳期的牛磺酸排泄模式进行了测量，并与在十名孕期杂食性女性中观察到的包括内源性牛磺酸前体在内的其他氨基酸尿排泄变化进行了比较。还测定了十四名杂食性母亲和十四名纯素食母亲母乳中牛磺酸的损失情况。与孕期包括蛋氨酸和半胱氨酸在内的所有氨基酸排泄量增加相反，所有受试者在孕期第9周时牛磺酸排泄量急剧下降，而在纯素食/素食受试者中，哺乳期时牛磺酸排泄量进一步下降。尽管纯素食受试者母乳中牛磺酸的浓度较低，但其平均值仍在杂食性受试者的范围内。我们的研究结果表明，孕期和哺乳期尿中牛磺酸排泄的抑制是对生殖的一种生理反应，可满足胎儿和哺乳婴儿对这种氨基酸的需求。数据还表明，牛磺酸在孕早期储存在母体组织中，以供后期转移给胎儿。
