Laidlaw S A, Shultz T D, Cecchino J T, Kopple J D
Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA 90509.
Am J Clin Nutr. 1988 Apr;47(4):660-3. doi: 10.1093/ajcn/47.4.660.
Plasma taurine levels and urinary taurine excretion were measured in 12 strict vegetarian (vegan) males who had maintained a vegan diet for 53 +/- 26 mo (SD) and in 14 male nonvegetarian control subjects. Plasma taurine levels differed (45 +/- 7 vs 58 +/- 16 mumol/L, respectively). Urinary taurine excretion was lower (266 +/- 279 vs 903 +/- 580 mumol/d), urinary N pi-methylhistidine was barely detectable, and urinary N tau-methylhistidine was significantly reduced (296 +/- 87 vs 427 +/- 19 mumol/d) in the vegans. Analysis of 3-d dietary diaries kept by the vegans indicated marginal to adequate intake of protein, carbohydrate, vitamin B-6, methionine, and cystine; inadequate intake of zinc; and negligible intake of taurine. Prolonged absence of dietary taurine intake causes decreased plasma taurine and severely restricted urinary taurine output.
对12名严格素食（纯素）男性进行了血浆牛磺酸水平和尿牛磺酸排泄量的测定，这些男性保持纯素饮食53±26个月（标准差），并与14名非素食男性对照者进行比较。血浆牛磺酸水平存在差异（分别为45±7与58±16μmol/L）。纯素者的尿牛磺酸排泄量较低（266±279与903±580μmol/天），尿N-π-甲基组氨酸几乎检测不到，尿N-τ-甲基组氨酸显著降低（296±87与427±19μmol/天）。对纯素者记录的3天饮食日记分析表明，蛋白质、碳水化合物、维生素B-6、蛋氨酸和胱氨酸的摄入量处于边缘充足到充足水平；锌摄入量不足；牛磺酸摄入量可忽略不计。长期缺乏饮食中牛磺酸的摄入会导致血浆牛磺酸水平降低和尿牛磺酸排出量严重受限。
