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俄克拉荷马州当地口罩令对 COVID-19 病例率的影响。

Impact of local mask mandates upon COVID-19 case rates in Oklahoma.

机构信息

Oklahoma State Department of Health, Oklahoma State University, Oklahoma City, Oklahoma, United States of America.

Oklahoma State University Department of Veterinary Pathobiology, Stillwater, OK, United States of America.

出版信息

PLoS One. 2022 Jun 16;17(6):e0269339. doi: 10.1371/journal.pone.0269339. eCollection 2022.

Abstract

Use of face coverings has been shown to reduce transmission of SARS-CoV-2. Despite encouragements from the CDC and other public health entities, resistance to usage of masks remains, forcing government entities to create mandates to compel use. The state of Oklahoma did not create a state-wide mask mandate, but numerous municipalities within the state did. This study compares case rates in communities with mandates to those without mandates, at the same time and in the same state (thus keeping other mitigation approaches similar). Diagnosed cases of COVID-19 were extracted from the Oklahoma State Department of Health reportable disease database. Daily case rates were established based upon listed city of residence. The daily case rate difference between each locality with a mask mandate were compared to rates for the portions of the state without a mandate. All differences were then set to a d0 point of reference (date of mandate implementation). Piecewise linear regression analysis of the difference in SARS-CoV-2 infection rates between mandated and non-mandated populations before and after adoption of mask mandates was then done. Prior to adopting mask mandates, those municipalities that eventually adopted mandates had higher transmission rates than the rest of the state, with the mean case rate difference per 100,000 people increasing by 0.32 cases per day (slope of difference = 0.32; 95% CI 0.13 to 0.51). For the post-mandate time period, the differences are decreasing (slope of -0.24; 95% CI -0.32 to -0.15). The pre- and post- mandate slopes differed significantly (p<0.001). The change in slope direction (-0.59; 95% CI -0.80 to -0.37) shows a move toward reconvergence in new case diagnoses between the two populations. Compared to rates in communities without mask mandates, transmission rates of SARS-CoV-2 slowed notably in those communities that adopted a mask mandate. This study suggests that government mandates may play a role in reducing transmission of SARS-CoV-2, and other infectious respiratory conditions.

摘要

佩戴口罩已被证明可以减少 SARS-CoV-2 的传播。尽管美国疾病控制与预防中心和其他公共卫生机构都在鼓励使用口罩,但人们仍然抵制使用口罩,这迫使政府部门制定强制使用口罩的规定。俄克拉荷马州没有颁布全州范围内的口罩强制令,但该州的许多市都颁布了。本研究比较了有口罩强制令和没有口罩强制令的社区的病例发生率,这些社区在同一时间和同一州(因此保持其他缓解措施相似)。从俄克拉荷马州卫生部门的法定传染病报告数据库中提取了 COVID-19 的确诊病例。根据列出的居住城市确定了每日病例数。将每个有口罩强制令的地方与没有口罩强制令的地方的每日病例率差异与没有口罩强制令的州部分的比率进行了比较。然后,将所有差异设置为 d0 参考点(强制令实施日期)。然后,对采用口罩强制令前后,受强制令和不受强制令影响的人群中 SARS-CoV-2 感染率的差异进行分段线性回归分析。在颁布口罩强制令之前,那些最终颁布强制令的城市的传播率高于该州的其他地区,每 10 万人的平均病例率差异每天增加 0.32 例(差异斜率=0.32;95%置信区间 0.13 至 0.51)。在强制令颁布后的时期,差异正在减少(斜率为-0.24;95%置信区间-0.32 至-0.15)。强制令颁布前后的斜率有显著差异(p<0.001)。斜率方向的变化(-0.59;95%置信区间-0.80 至-0.37)表明,两个群体之间的新病例诊断趋同。与没有口罩强制令的社区相比,实施口罩强制令的社区中 SARS-CoV-2 的传播速度明显放缓。本研究表明,政府强制令可能在减少 SARS-CoV-2 及其他传染性呼吸道疾病的传播方面发挥作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9365/9202880/8227c4996e78/pone.0269339.g001.jpg

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