Shahbaz Alam Md, Dhiman Arjun, Jain Veena, Bhutia Ongkila, Pruthi Gunjan
Center for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, 110029 India.
Department of Prosthodontics, CDER, AIIMS, New Delhi, 110029 India.
J Maxillofac Oral Surg. 2022 Jun;21(2):533-541. doi: 10.1007/s12663-020-01426-8. Epub 2020 Jul 28.
Various graft materials have been studied for filling peri-implant gap (PIG), but there was no similar randomized clinical trial to evaluate the effect of Platelet-rich fibrin or alloplast or their combination on vertical bone implant contact (BIC) around immediate implants and their stability over a period of 1 year.
Immediate implants were placed in maxillary anterior region of 30 subjects ( = 10). Either alloplast (group I) or L-PRF (group II) or both (group III) were used to fill the PIG following randomization chart. Vertical BIC was measured on peri-apical radiographs which were taken immediately after placement, after 3, 6 and 12 months using Image J software. Periotest was used to measure the implant stability at the time of implant placement, at 3, 6 and 12 months after implantation.
The comparison of distance from implant shoulder to the first visible bone-to-implant contact (IS-BIC) in each group showed statistically significant bone formation on mesial and distal sides over a 1 year period ( < 0.05). There was no significant difference in IS-BIC distance among the three groups at 1 year ( > 0.05). Periotest values showed that there was significant improvement in implant stability in all groups in 1-year period. On intergroup comparison, the mean difference of periotest values was statistically non-significant among three groups ( > 0.05).
All the graft materials were effective in promoting osseointegration when used as PIG filling materials alone or in combination around immediate implants in maxillary anterior region.
REF/2015/06/009200.
已对多种移植材料用于填充种植体周围间隙（PIG）进行了研究，但尚无类似的随机临床试验来评估富血小板纤维蛋白或异体材料或其组合对即刻种植体周围垂直骨种植体接触（BIC）及其在1年期间稳定性的影响。
在30名受试者（每组 = 10）的上颌前部区域植入即刻种植体。按照随机图表，使用异体材料（I组）或L-PRF（II组）或两者（III组）来填充PIG。使用Image J软件，在种植体植入后即刻、3个月、6个月和12个月时拍摄根尖周X光片，测量垂直BIC。在种植体植入时、植入后3个月、6个月和12个月，使用Periotest测量种植体稳定性。
每组中从种植体肩部到首次可见骨与种植体接触（IS-BIC）的距离比较显示，在1年期间，近中和远中侧均有统计学意义的骨形成（P < 0.05）。1年时，三组之间的IS-BIC距离无显著差异（P > 0.05）。Periotest值显示，所有组在1年期间种植体稳定性均有显著改善。组间比较时，三组之间Periotest值的平均差异无统计学意义（P > 0.05）。
当单独或联合用作上颌前部区域即刻种植体周围的PIG填充材料时，所有移植材料在促进骨整合方面均有效。
CTRI编号：REF/2015/06/009200。
