Department of Dermatology, Seoul National University Bundang Hospital, 82 Gumi-Ro 173 Beon-Gil, Seongnam, 13620, Gyeonggi, Korea.
Sci Rep. 2022 Jun 17;12(1):10183. doi: 10.1038/s41598-022-14533-y.
Basal cell carcinoma (BCC) affecting different sites has been reported to have different clinicopathological features. In previous studies, the scalp was commonly classified to the head and neck region. However, the scalp has distinct characteristics from those of other parts of the skin. We retrospectively reviewed the medical records of patients who underwent surgical treatment for BCC. A total of 734 lesions were examined, and 13.2% originated from the scalp. The nodular type was the most common histologic subtype; however, the proportion of the superficial type was significantly higher than that of facial BCC (p < 0.001). Compared with facial BCC, younger age (p = 0.046) and larger tumor size (p < 0.001) were observed in scalp BCC. These characteristics were similar to those of truncal BCC in that they demonstrated a higher proportion of the superficial type (p < 0.001), younger age (p = 0.001), and larger tumor diameter (p < 0.001) compared with BCC in the head and neck region. Scalp BCC and truncal BCC were not significantly different in terms of age (p = 0.052) and tumor size (p = 0.230). In conclusion, despite the anatomical proximity, features of scalp BCC were similar to those of truncal lesions compared with facial lesions. Scalp BCC might be a separate entity from facial BCC.
基底细胞癌（BCC）影响不同部位，其临床病理特征也不同。在以前的研究中，头皮通常被归类到头颈部。然而，头皮与其他皮肤部位有明显的不同。我们回顾性地审查了接受 BCC 手术治疗的患者的病历。共检查了 734 个病变，其中 13.2%起源于头皮。结节型是最常见的组织学亚型；然而，浅表型的比例明显高于面部 BCC（p<0.001）。与面部 BCC 相比，头皮 BCC 患者年龄更小（p=0.046），肿瘤直径更大（p<0.001）。这些特征与躯干 BCC 相似，与头颈部 BCC 相比，它们表现出更高比例的浅表型（p<0.001）、更年轻的年龄（p=0.001）和更大的肿瘤直径（p<0.001）。头皮 BCC 和躯干 BCC 在年龄（p=0.052）和肿瘤大小（p=0.230）方面无显著差异。总之，尽管解剖位置接近，但与面部病变相比，头皮 BCC 的特征与躯干病变相似。头皮 BCC 可能与面部 BCC 是不同的实体。
