Cancer Registration and Statistic Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Department of Preventive Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Cancer Res Treat. 2018 Jul;50(3):729-737. doi: 10.4143/crt.2017.166. Epub 2017 Jul 14.
This descriptive study was aimed to examine trends in the incidence of melanoma and nonmelanoma in South Korea.
The nationwide incidence data for melanoma and non-melanoma skin cancer was obtained from the Korea Central Cancer Registry. Age-standardized rates were calculated and analyzed, using a Joinpoint regression model.
The incidence of basal cell carcinoma has increased dramatically both in men (average annual percentage change [AAPC], 8.0 [95% confidence interval (CI), 6.0 to 10.1]) and women (AAPC, 9.0 [95% CI, 7.5 to 10.4]). Squamous cell carcinoma has also steadily increased both in men (AAPC, 3.3 [95% CI, 2.6 to 4.0]) and women (AAPC, 6.8 [95% CI, 5.3 to 8.4]). Cutaneous melanoma increased continuously from 1999 to 2014 inwomen (AAPC, 3.5 [95% CI, 2.4 to 4.6]), whilst rapidly increasing in men until 2005 (APC, 7.9 [95% CI, 2.4 to 13.7]) after which no increase has been observed (APC, ‒0.2 [95% CI, ‒2.3 to 2.0]).
The incidence rates of melanoma and non-melanoma skin cancer have increased over the past years, with the exception of melanoma in men. Further studies are required to investigate the reasons for the increased incidence of these skin cancers in South Korea.
本描述性研究旨在探讨韩国黑色素瘤和非黑色素瘤发病率的变化趋势。
从韩国中央癌症登记处获取黑色素瘤和非黑色素瘤皮肤癌的全国发病率数据。使用 Joinpoint 回归模型计算和分析年龄标准化率。
基底细胞癌的发病率在男性（平均年变化百分比 [AAPC]，8.0 [95%置信区间 [CI]，6.0 至 10.1]）和女性（AAPC，9.0 [95% CI，7.5 至 10.4]）中均显著增加。鳞状细胞癌在男性（AAPC，3.3 [95% CI，2.6 至 4.0]）和女性（AAPC，6.8 [95% CI，5.3 至 8.4]）中也呈稳步上升趋势。从 1999 年到 2014 年，女性的皮肤黑色素瘤持续增加（AAPC，3.5 [95% CI，2.4 至 4.6]），而男性的发病率在 2005 年前迅速增加（APC，7.9 [95% CI，2.4 至 13.7]），此后未再增加（APC，-0.2 [95% CI，-2.3 至 2.0]）。
过去几年，黑色素瘤和非黑色素瘤皮肤癌的发病率有所上升，除了男性黑色素瘤。需要进一步研究以探讨韩国这些皮肤癌发病率增加的原因。
