Department of Surgery, Minimally Invasive Surgery Research Center, Division of Minimally Invasive and Bariatric Surgery, Rasool-E Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Center of Excellence of European Branch of International Federation for Surgery of Obesity, Hazrat_e Rasool Hospital, Tehran, Iran.
Sci Rep. 2022 Jun 18;12(1):10304. doi: 10.1038/s41598-022-14633-9.
The most accepted procedures as conversion for poor weight changes after sleeve gastrectomy (SG), are malabsorptive surgeries. This study was designed to evaluate the 5-year outcomes of One Anastomosis Gastric Bypass (OAGB) following SG due to weight loss failure and weight regain. From September 2014 to January 2017, totally 23 patients with a history of SG conversion to OAGB in terms of weight loss failure or weight regain who had completed their 5-year follow-ups were studied. Some obesity related co-morbidities containing type-2 diabetes (DM), hypertension (HTN), dyslipidemia, obstructive sleep apnea (OSA) and gastroesophageal reflux disease (GERD) were also investigated at 1, 2, 3 and 5 years after conversional surgery. All cases had remission/improvement in DM, DLP, HTN and OSA 1 year after conversional OAGB. Analysis showed statistically significant (P < 0.001) change in trend of BMI. Mean BMI before conversional surgery, at 1, 2, 3and 5 years were 46.3 ± 10.4, 34.5 ± 8.5, 34.1 ± 8.6, 35.7 ± 8.7 and 37.5 ± 11.6, respectively. Mean percent excess weight loss (%EWL) at 1, 2, 3 and 5 years was 51.6 ± 11.0, 52.9 ± 13.1, 45.5 ± 16.4 and 41.0 ± 18.0, respectively. Mean percent total weight loss (%TWL) at 1, 2, 3 and 5 years was 26.6 ± 5.9, 27.4 ± 7.2, 23.9 ± 9.2 and 20.9 ± 9.3, respectively. OAGB is an effective conversional procedure for insufficient weight loss and weight regain following failed SG and lead to satisfactory changes in obesity associated medical problems. The optimal weight loss results are obtained at 2-year follow-ups and these effects are then reduced.
胃旁路手术（OAGB）是治疗袖状胃切除术后（SG）体重减轻失败和体重反弹的最常用方法。本研究旨在评估 23 例 SG 后因减重失败或体重反弹而改行 OAGB 的患者 5 年随访结果。2014 年 9 月至 2017 年 1 月，对 23 例 SG 术后体重减轻失败或体重反弹患者进行了 OAGB 手术。研究还在术后 1、2、3 和 5 年时评估了与肥胖相关的合并症，包括 2 型糖尿病（DM）、高血压（HTN）、血脂异常、阻塞性睡眠呼吸暂停（OSA）和胃食管反流病（GERD）。所有患者在接受 OAGB 手术后 1 年，DM、DLP、HTN 和 OSA 均有缓解/改善。分析显示，BMI 呈显著（P < 0.001）变化趋势。术前、术后 1、2、3 和 5 年的 BMI 分别为 46.3 ± 10.4、34.5 ± 8.5、34.1 ± 8.6、35.7 ± 8.7 和 37.5 ± 11.6。术后 1、2、3 和 5 年的 EWL 百分比分别为 51.6 ± 11.0、52.9 ± 13.1、45.5 ± 16.4 和 41.0 ± 18.0。术后 1、2、3 和 5 年的 TWL 百分比分别为 26.6 ± 5.9、27.4 ± 7.2、23.9 ± 9.2 和 20.9 ± 9.3。OAGB 是治疗 SG 后体重减轻不足和体重反弹的有效转化方法，可导致肥胖相关医疗问题得到满意改善。最佳减肥效果在术后 2 年随访时获得，随后效果降低。
