Department of Respiratory Medicine, First People's Hospital of Fuyang District, Hangzhou, 311400 Zhejiang, China.
Comput Math Methods Med. 2022 Jun 9;2022:3585567. doi: 10.1155/2022/3585567. eCollection 2022.
The objective of this study was to investigate the intervention effect of computed tomography (CT) image information data on patients with advanced lung cancer treated with chemotherapy under palliative care program. The research subjects were 60 patients with advanced lung cancer who received palliative care in our hospital from January 1, 2019, to January 1, 2021. All patients were grouped according to the evaluation criteria of solid tumor efficacy, including 28 patients in the remission group and 32 patients in the nonremission group. Texture analysis was performed on the CT images of the two groups of patients. The gray-scale cooccurrence matrix parameters, the maximum diameter of the lesion, and the CT value of the CT images of the two groups of patients before and after palliative care were compared. The results showed that after the palliative care, the combined mean, combined energy, and inverse moment of the three gray cooccurrence matrix parameters of the two groups of patients were decreased, and the combined entropy and contrast were increased. The absolute value of the gray-scale cooccurrence matrix Δ parameter of the patients in the remission group was greater than that in the nonremission group. The Δ combined entropy, Δ contrast, and Δ correlation of the two groups of patients were significantly different, and the difference in Δ contrast was the largest. It suggested that the gray-scale cooccurrence matrix parameter can evaluate the effect of soothing care, and the contrast was the best evaluation parameter. The maximum diameter of the lesions in the remission group before and after palliative care was reduced by 1.23 cm, and the degree of reduction was significantly better. The CT value was reduced by 6.22 HU, and the degree of reduction was significantly higher than that in the nonremission group. There was a significant difference in the data between the two groups ( < 0.05). Therefore, the CT image information data had a better evaluation effect on patients with advanced lung cancer under the palliative care program and can be applied to the clinical evaluation of the palliative care effect, which had good clinical value.
本研究旨在探讨计算机断层扫描(CT)图像信息数据对接受姑息治疗方案的晚期肺癌化疗患者的干预效果。研究对象为 2019 年 1 月 1 日至 2021 年 1 月 1 日期间在我院接受姑息治疗的 60 例晚期肺癌患者。所有患者均根据实体瘤疗效评价标准进行分组,其中缓解组 28 例,未缓解组 32 例。对两组患者的 CT 图像进行纹理分析,比较两组患者 CT 图像的灰度共生矩阵参数、病灶最大直径及 CT 值。结果显示,姑息治疗后,两组患者的灰度共生矩阵三个参数的联合均值、联合能量和逆矩均降低,联合熵和对比度升高;缓解组患者的灰度共生矩阵Δ参数绝对值大于未缓解组,两组患者的Δ联合熵、Δ对比度和Δ相关度差异均有统计学意义,且以Δ对比度差异最大。提示灰度共生矩阵参数可评估姑息治疗效果,对比度为最佳评价参数。缓解组患者姑息治疗前后病灶最大直径缩小 1.23cm,缩小程度明显较好;CT 值降低 6.22HU,降低程度明显高于未缓解组,两组数据比较差异均有统计学意义(<0.05)。因此,CT 图像信息数据对姑息治疗方案下的晚期肺癌患者具有较好的评价效果,可应用于姑息治疗效果的临床评价,具有较好的临床应用价值。