Singh Pramod Kumar, Srivastava Resham, Kumar Ishan, Rai Sangeeta, Pandey Saurabh, Shukla Ram C, Verma Ashish
Department of Radiodiagnosis and Imaging, IMS, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Department of Obstetrics and Gynaecology, IMS, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Indian J Radiol Imaging. 2022 Feb 28;32(1):10-15. doi: 10.1055/s-0041-1741411. eCollection 2022 Mar.
The aim of this article was to evaluate uterocervical angle (UCA) and cervical length (CL) measured at 16 to 24 weeks of gestation using transvaginal sonography (TVS) as predictors of spontaneous preterm birth. In this prospective study, TVS was performed in 159 primigravidas with a singleton, uncomplicated pregnancy at 16 to 24 weeks of gestation to measure the anterior UCA and CL. All the cases were followed until labor to document gestational age at delivery. The risk of spontaneous preterm birth was higher in women with obtuse UCA (>95 degrees) with sensitivity of 86.7%, specificity of 93.0%, positive predictive value of 83.0%, negative predictive value of 94.6%, and -value of <0.001. The difference between the means was statistically significant ( -value < 0.001). UCAs ≥105degrees and 95 to 105 degrees were found to be significantly associated with spontaneous preterm births at <34 weeks and 34 to 37 weeks, respectively. CL <2.5 cm was found to predict spontaneous preterm births at <37 weeks with sensitivity of 31.1%, specificity of 95.6%, and -value of <0.001. UCA was found to be a better predictor of spontaneous preterm birth with a higher coefficient of variation (56.4%) when compared with CL (16.9%). UCA proved to be a novel ultrasound parameter that can serve as a better predictor of spontaneous preterm births in comparison to CL. A strong correlation exists between obtuse UCA and a risk of spontaneous preterm birth.
本文旨在评估经阴道超声检查(TVS)在妊娠16至24周时测量的子宫颈角度(UCA)和宫颈长度(CL)作为自发性早产预测指标的价值。
在这项前瞻性研究中,对159名单胎、无并发症妊娠的初产妇在妊娠16至24周时进行TVS检查,以测量前位UCA和CL。所有病例均随访至分娩,记录分娩时的孕周。
UCA为钝角(>95°)的女性发生自发性早产的风险更高,其敏感性为86.7%,特异性为93.0%,阳性预测值为83.0%,阴性预测值为94.6%,P值<0.001。均值之间的差异具有统计学意义(P值<0.001)。发现UCA≥105°和95至105°分别与<34周和34至37周的自发性早产显著相关。发现CL<2.5 cm可预测<37周的自发性早产,敏感性为31.1%,特异性为95.6%,P值<0.001。与CL(16.9%)相比,UCA被发现是自发性早产的更好预测指标,变异系数更高(56.4%)。
与CL相比,UCA被证明是一种新型超声参数,可作为自发性早产的更好预测指标。钝角UCA与自发性早产风险之间存在很强的相关性。