van Wyk T C, Berry H H
J S Afr Vet Assoc. 1986 Dec;57(4):221-4.
A combination of ketamine at 8.0 mg/kg and xylazine at 3.2 mg/kg was found effective in immobilising lions (Panthera leo) for 4 hours. Ataxia and immobilisation were rapidly induced, with stable respiratory rate, heart rate and body temperature recorded. Tolazoline effectively antagonised xylazine via intravenous or intramuscular injection, resulting in a return to mobility within approximately 20 and 60 minutes, respectively. Tolazoline also elevated the respiratory rate. No mortalities occurred during 97 immobilisations of 76 lions.
已发现，8.0毫克/千克的氯胺酮与3.2毫克/千克的甲苯噻嗪联合使用，能有效使狮子（豹属狮种） immobilise达4小时。共济失调和immobilisation迅速诱发，记录到呼吸频率、心率和体温稳定。托拉唑啉通过静脉注射或肌肉注射有效拮抗甲苯噻嗪，分别导致在约20分钟和60分钟内恢复活动能力。托拉唑啉还提高了呼吸频率。在对76头狮子进行的97次immobilisations过程中未发生死亡。
