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COVID-19 对接受减重手术患者的中期减重和合并症的影响及其与心理健康的关系。

The impact of COVID-19 on medium term weight loss and comorbidities in patients undergoing bariatric surgery and its association with psychological wellbeing.

机构信息

Roy J. and Lucille A. Carver College of Medicine, MIS, Bariatric and GI Surgery, 200 Hawkins Drive 4634 JCP, Iowa City, IA, 52242-1086, USA.

出版信息

Surg Endosc. 2023 Feb;37(2):1537-1542. doi: 10.1007/s00464-022-09377-6. Epub 2022 Jun 22.

Abstract

BACKGROUND

The COVID-19 epidemic imposed significant stressors on individuals and changed how medical care is delivered. The affect that this stress has placed on the field of bariatric surgery and the associated outcomes is not well established.

METHODS

A retrospective review of a prospectively collected database from a single academic institution was conducted. Weight loss and comorbidity outcomes were compared between a cohort of patients operated on during the pandemic and a matched group operated on prior to COVID-19. GAD-7 and PHQ-9 questionnaires were used to assess for anxiety and depression, respectively.

RESULTS

A total of 329 and 155 patients were enrolled in the pre-pandemic and COVID-19 groups respectively. There were no significant differences in pre-operative BMI (p = 0.437) or comorbidities: Type II DM (p = 0.810), hypertension (p = 0.879), sleep apnea (p = 0.502), and hyperlipidemia (p = 0.227). Post-operatively, weight loss was comparable at all time points out to 1 year. Type II DM resolution rates were higher in the control cohort at 6 months (p = 0.007), but not at 12 months (p = 1.000). There was no statistically significant difference in resolution rates between the control group and the COVID-19 group for the other measured comorbidities. There was no difference in objective measures of anxiety and depression when comparing the two groups (both p > 0.05).

CONCLUSIONS

The COVID-19 pandemic has fundamentally changed how society and medical systems function. Focusing on pre-operative dietary training and screening for inadequately managed psychological comorbidities yielded similar weight loss outcomes notwithstanding the significant societal and individual stressors with which patients were faced.

摘要

背景

COVID-19 大流行给个人带来了巨大压力,并改变了医疗服务的提供方式。这种压力对减重手术领域及其相关结果的影响尚未得到充分证实。

方法

对一家学术机构前瞻性收集的数据库进行回顾性分析。比较了大流行期间手术的患者队列和 COVID-19 之前手术的匹配组的减肥和合并症结果。使用 GAD-7 和 PHQ-9 问卷分别评估焦虑和抑郁情况。

结果

共有 329 名和 155 名患者分别入组于大流行前组和 COVID-19 组。两组患者的术前 BMI(p=0.437)或合并症无显著差异:2 型糖尿病(p=0.810)、高血压(p=0.879)、睡眠呼吸暂停(p=0.502)和高脂血症(p=0.227)。术后所有时间点的减重效果相似,最长达 1 年。在 6 个月时,对照组的 2 型糖尿病缓解率更高(p=0.007),但在 12 个月时无差异(p=1.000)。对于其他测量的合并症,对照组和 COVID-19 组的缓解率没有统计学差异。比较两组时,焦虑和抑郁的客观指标无差异(均 p>0.05)。

结论

COVID-19 大流行从根本上改变了社会和医疗系统的运作方式。尽管患者面临着巨大的社会和个人压力,但关注术前饮食训练和筛查未得到充分治疗的心理合并症,仍可获得相似的减重效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad3e/9215154/161d60da121a/464_2022_9377_Fig1_HTML.jpg

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